Near-infrared (NIR) fluorescence-emitting small organic molecules for cancer imaging and therapy

H Li, Y Kim, H Jung, JY Hyun, I Shin - Chemical Society Reviews, 2022 - pubs.rsc.org
Near-infrared (NIR) fluorophores have unique features that endow them with several
advantages over conventional shorter wavelength emitting dyes. As a result, they have been …

Recent advances in nanomaterial‐based nanoplatforms for chemodynamic cancer therapy

SL Li, P Jiang, FL Jiang, Y Liu - Advanced Functional Materials, 2021 - Wiley Online Library
Triggered by the endogenous chemical energy in the tumor microenvironment (TME),
chemodynamic therapy (CDT) as an emerging non‐exogenous stimulant therapeutic …

[HTML][HTML] Gas therapy potentiates aggregation-induced emission luminogen-based photoimmunotherapy of poorly immunogenic tumors through cGAS-STING pathway …

K Wang, Y Li, X Wang, Z Zhang, L Cao, X Fan… - Nature …, 2023 - nature.com
The immunologically “cold” microenvironment of triple negative breast cancer results in
resistance to current immunotherapy. Here, we reveal the immunoadjuvant property of gas …

Recent advances on modulation of H2O2 in tumor microenvironment for enhanced cancer therapeutic efficacy

Z Chu, J Yang, W Zheng, J Sun, W Wang… - Coordination Chemistry …, 2023 - Elsevier
Due to the rapid proliferation of tumors, the hydrogen peroxide (H 2 O 2) concentration of
tumor cells is higher than that of normal cells, which can be used as an effective target for …

Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Porphyrin‐based metal–organic frameworks for biomedical applications

J Chen, Y Zhu, S Kaskel - Angewandte Chemie International …, 2021 - Wiley Online Library
Porphyrins and porphyrin derivatives have been widely explored for various applications
owing to their excellent photophysical and electrochemical properties. However, inherent …

[HTML][HTML] A hydrogen sulphide-responsive and depleting nanoplatform for cancer photodynamic therapy

Y Zhang, J Fang, S Ye, Y Zhao, A Wang, Q Mao… - Nature …, 2022 - nature.com
Hydrogen sulfide (H2S) as an important biological gasotransmitter plays a pivotal role in
many physiological and pathological processes. The sensitive and quantitative detection of …

X‐ray‐Induced release of nitric oxide from hafnium‐based nanoradiosensitizers for enhanced radio‐immunotherapy

N Liu, J Zhu, W Zhu, L Chen, M Li, J Shen… - Advanced …, 2023 - Wiley Online Library
Radiotherapy (RT) is an extensively used strategy for cancer treatment, but its therapeutic
effect is usually limited by the abnormal tumor microenvironment (TME) and it lacks the …

[HTML][HTML] Hydrogen sulfide: An endogenous regulator of the immune system

N Dilek, A Papapetropoulos, T Toliver-Kinsky… - Pharmacological …, 2020 - Elsevier
Hydrogen sulfide (H 2 S) is now recognized as an endogenous signaling gasotransmitter in
mammals. It is produced by mammalian cells and tissues by various enzymes …

NBD-based synthetic probes for sensing small molecules and proteins: design, sensing mechanisms and biological applications

C Jiang, H Huang, X Kang, L Yang, Z Xi… - Chemical Society …, 2021 - pubs.rsc.org
Compounds with a nitrobenzoxadiazole (NBD) skeleton exhibit prominent useful properties
including environmental sensitivity, high reactivity toward amines and biothiols (including …