[HTML][HTML] Intestinal barrier damage, systemic inflammatory response syndrome, and acute lung injury: A troublesome trio for acute pancreatitis

P Ge, Y Luo, CS Okoye, H Chen, J Liu, G Zhang… - Biomedicine & …, 2020 - Elsevier
Severe acute pancreatitis (SAP), a serious inflammatory disease of the pancreas, can easily
lead to systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction …

[HTML][HTML] The role of M6A modification in the regulation of tumor-related lncRNAs

Y Lan, B Liu, H Guo - Molecular Therapy-Nucleic Acids, 2021 - cell.com
N 6-methyladenosine (m 6 A) is the most abundant modification in eukaryotic cells, and it
regulates RNA transcription, processing, splicing, degradation, and translation. Long non …

[HTML][HTML] ALKBH5-mediated m6A demethylation of KCNK15-AS1 inhibits pancreatic cancer progression via regulating KCNK15 and PTEN/AKT signaling

Y He, HQ Yue, Y Cheng, Z Ding, Z Xu, C Lv… - Cell death & …, 2021 - nature.com
Long noncoding RNAs (lncRNAs) are regarded as crucial regulators in tumor progression.
Potassium two pore domain channel subfamily K member 15 and WISP2 antisense RNA 1 …

[HTML][HTML] Treatment of SARS-CoV-2-induced pneumonia with NAD+ and NMN in two mouse models

Y Jiang, Y Deng, H Pang, T Ma, Q Ye, Q Chen, H Chen… - Cell Discovery, 2022 - nature.com
The global COVID-19 epidemic has spread rapidly around the world and caused the death
of more than 5 million people. It is urgent to develop effective strategies to treat COVID-19 …

A novel pyroptosis-related lncRNA signature for predicting the prognosis of skin cutaneous melanoma

J Xie, H Li, L Chen, Y Cao, Y Hu, Z Zhu… - … Journal of General …, 2021 - Taylor & Francis
Purpose To construct a prognosis model of melanoma based on pyroptosis related genes.
Methods Melanoma RNA-sequencing data was downloaded from TCGA. First, the lnRNAs …

The various regulatory functions of long noncoding RNAs in apoptosis, cell cycle, and cellular senescence

M Heydarnezhad Asl… - Journal of cellular …, 2022 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are a group of noncoding cellular RNAs involved in
significant biological phenomena such as differentiation, cell development, genomic …

Short open reading frame genes in innate immunity: from discovery to characterization

E Malekos, S Carpenter - Trends in immunology, 2022 - cell.com
Next-generation sequencing (NGS) technologies have greatly expanded the size of the
known transcriptome. Many newly discovered transcripts are classified as long noncoding …

[HTML][HTML] Noncoding RNAs related to the hedgehog pathway in cancer: clinical implications and future perspectives

J Song, Y Ge, X Sun, Q Guan, S Gong, M Wei, J Niu… - Molecular cancer, 2022 - Springer
Cancer is a type of malignant affliction threatening human health worldwide; however, the
molecular mechanism of cancer pathogenesis remains to be elusive. The oncogenic …

[HTML][HTML] Lnc Tmem235 promotes repair of early steroid-induced osteonecrosis of the femoral head by inhibiting hypoxia-induced apoptosis of BMSCs

F Zhang, W Peng, T Wang, J Zhang, W Dong… - … & Molecular Medicine, 2022 - nature.com
Bone marrow mesenchymal stem cells (BMSCs) have been used in the treatment of early
steroid-induced osteonecrosis of the femoral head (SONFH). However, the hypoxic …

[HTML][HTML] Long noncoding RNAs in neurodegenerative diseases: pathogenesis and potential implications as clinical biomarkers

M Zhang, P He, Z Bian - Frontiers in Molecular Neuroscience, 2021 - frontiersin.org
Neurodegenerative diseases (NDDs), including Alzheimer's disease (AD), Parkinson's
disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS), are …