Osteoarthritis (OA) is a highly prevalent whole-joint disease that causes disability and pain
and affects a patient's quality of life. However, currently, there is a lack of effective early …

Knee osteoarthritis (KOA) is the most common form of joint degeneration with increasing
prevalence and incidence in recent decades. KOA is a molecular disorder characterized by …

Osteoarthritis (OA) is a disease of the whole joint organ, characterized by the loss of
cartilage, and structural changes in bone including the formation of osteophytes, causing …

Understanding the causality of the post-traumatic osteoarthritis (PTOA) disease process of
the knee joint is important for diagnosing early disease and developing new and effective …

Objective In this review, we have highlighted the advances over the past year in genetics,
genomics and epigenetics in the field of osteoarthritis (OA). Methods A literature search of …

Objective To summarize recent scientific advances in protein-derived soluble biomarkers of
osteoarthritis. Design A systematic search on the PubMed electronic database of clinical …

Purpose To provide an updated review of the literature on the use of orthobiologics as a
potential treatment option to alleviate symptoms associated with osteoarthritis (OA), slow the …

Objectives The aim of this study was to identify biomarkers for radiographic OA severity and
progression acting within the inflammation and metabolic pathways. Methods For 3517 …

In this narrative review article, we critically assess the current state of the osteoarthritis (OA)
drug development pipeline. We discuss the current state-of-the-art in relation to the …

Biomarkers, especially biochemical markers, are important in osteoarthritis (OA) research,
clinical trials, and drug development and have potential for more extensive use in …