Hepatitis B virus (HBV) is a non-cytopathic, hepatotropic virus with the potential to cause a
persistent infection, ultimately leading to cirrhosis and hepatocellular carcinoma. Over the …

Approximately 5% of individuals infected with hepatitis B virus (HBV) are coinfected with
hepatitis D virus (HDV). Chronic HBV/HDV coinfection is associated with an unfavourable …

Functional cure of hepatitis B is defined as sustained undetectable circulating HBsAg and
HBV DNA after a finite course of treatment. Barriers to HBV cure include the reservoirs for …

A quaternary carbon bears four other carbon substituents or combination of four non-
hydrogen substituents at four vertices of a tetrahedron. The spirocyclic quaternary carbon …

Chronic hepatitis B virus (HBV) infection is a global public health challenge on the same
scale as tuberculosis, HIV, and malaria. The International Coalition to Eliminate HBV (ICE …

Globally, 296 million people are infected with hepatitis B virus (HBV), and approximately one
million people die annually from HBV-related causes, including liver cancer. Although there …

Hepatitis B virus (HBV) infection remains a global public health problem with changing
epidemiology due to several factors including vaccination policies and migration. This …

Background & Aims To evaluate the hypothesis that increasing T cell frequency and activity
may provide durable control of hepatitis B virus (HBV), we administered nivolumab, a …

Hepatitis B virus (HBV) infection causes chronic hepatitis and has long term complications.
Individuals ever infected with HBV are at risk of viral reactivation under certain …

B cells are increasingly recognized as playing an important role in the ongoing control of
hepatitis B virus (HBV). The development of antibodies against the viral surface antigen …