Determinants of p53 DNA binding, gene regulation, and cell fate decisions
M Fischer, MA Sammons - Cell Death & Differentiation, 2024 - nature.com
The extent to which transcription factors read and respond to specific information content
within short DNA sequences remains an important question that the tumor suppressor p53 is …
within short DNA sequences remains an important question that the tumor suppressor p53 is …
Gene regulation by the tumor suppressor p53–The omics era
M Fischer - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2024 - Elsevier
The transcription factor p53 is activated in response to a variety of cellular stresses and
serves as a prominent and potent tumor suppressor. Since its discovery, we have sought to …
serves as a prominent and potent tumor suppressor. Since its discovery, we have sought to …
The genome in space and time comes of age
M Rey-Millet, K Bystricky… - 2024 - Taylor & Francis
ABSTRACT DNA sequencing is not enough to grasp the complexity of genome organization
and function. The four-dimensional (three in space, one in time) configuration of the …
and function. The four-dimensional (three in space, one in time) configuration of the …