Fluorescent probes-illuminate the interplay network between lipid droplets and other organelles

J Yang, J Ning, P Sun, Y Nie, Y Li, M Guo… - Coordination Chemistry …, 2024 - Elsevier
Lipid droplets, as the centre of lipid metabolism, interact with the endoplasmic reticulum,
mitochondria, lysosome, nucleus and other organelles to maintain the body's energy …

Mechanistic analysis of viscosity-sensitive fluorescent probes for applications in diabetes detection

MM Sreejaya, VM Pillai, A Ayesha, M Baby… - Journal of Materials …, 2024 - pubs.rsc.org
Diabetes is one of the most detrimental diseases affecting the human life because it can
initiate several other afflictions such as liver damage, kidney malfunctioning, and cardiac …

Dual-Functional AIE Fluorescent Probe for Visualization of Lipid Droplets and Photodynamic Therapy of Cancer

S Pei, H Li, L Chen, G Nie, H Wang, C Liu… - Analytical …, 2024 - ACS Publications
Abnormal lipid droplets (LDs) are known to be intimately bound with the occurrence and
development of cancer, allowing LDs to be critical biomarkers for cancers. Aggregation …

Revealing the elevation of Zn 2+ in the brain of depressed mice by a ratiometric fluorescent probe with dual near-infrared emissions

H Jin, C Ju, C Duan, N Zhang, Y Cao, Q Xia… - Chemical …, 2024 - pubs.rsc.org
A mitochondria-targeted ratiometric fluorescent probe (Mito-Zn) was first designed and
synthesized with dual emissions both located in the near-infrared region, for Zn2+ detection …

A dual-functional fluorescence probe for detection of Aβ aggregates and hydroxyl radicals

Y An, X Luo, S Wei, J Lv, J Gao, X Li, M Yang… - Sensors and Actuators B …, 2023 - Elsevier
Synchronous detection of Aβ aggregates and reactive oxygen species (ROS) would provide
direct insight to reveal the complicated correlations between the two crucial Alzheimer's …

Lipid droplet-specific near-infrared fluorescent probe for discriminating cancer and normal cells and diagnosing fatty liver

Y Zhang, H Zhao, J Tang, S Nan, L Lu, P Zhang… - Bioorganic …, 2023 - Elsevier
Lipid droplets (LDs) is a newly essential organelle, which participates in carious
physiological and pathological processes. LDs are considered as potential markers for …

A new lysosome-targeted Cys probe and its application in biology and food samples

Y Zhang, C Xu, H Sun, J Ai, M Ren, F Kong - Spectrochimica Acta Part A …, 2024 - Elsevier
Cysteine (Cys) is a sulfur-containing amino acid that plays an important role in living
systems. The most common way to supplement the body with exogenous Cys is through the …

A novel near-infrared fluorescent probe for ultrasensitive and visual detection of mitochondrial viscosity

W Liu, T Wang, L Wang, Y Wang, S Hu… - Spectrochimica Acta Part A …, 2024 - Elsevier
The development of fluorescent probes capable of detecting abnormal changes in cellular
mitochondrial viscosity is of great significance, as these changes have been connected to …

The preparation of Golgi apparatus-targeted polymer dots encapsulated with carbon nanodots of bright near-infrared fluorescence for long-term bioimaging

Y Lu, W Song, Z Tang, W Shi, S Gao, J Wu, Y Wang… - Molecules, 2023 - mdpi.com
As a vital organelle in eukaryotic cells, the Golgi apparatus is responsible for processing and
transporting proteins in cells. Precisely monitoring the status of the Golgi apparatus with …

Monitoring the Mitochondrial Viscosity Changes During Cuproptosis with Iridium(III) Complex Probe via In Situ Phosphorescence Lifetime Imaging

GG Yang, YQ Zhao, L Zhang, S Sun, B Liu… - Analytical …, 2024 - ACS Publications
Cuproptosis is a novel copper-dependent form of programmed cell death, displaying
important regulatory functions in many human diseases, including cancer. However, the …