Genetics of the polycystic ovary syndrome

G Kosova, M Urbanek - Molecular and cellular endocrinology, 2013 - Elsevier
Polycystic ovary syndrome (PCOS) is a highly complex endocrine disorder, characterized by
hyperandrogenemia, menstrual irregularities and polycystic ovaries. A strong genetic …

Ethnic differences in the phenotypic expression of polycystic ovary syndrome

Y Zhao, J Qiao - Steroids, 2013 - Elsevier
Polycystic ovary syndrome (PCOS) is the most common endocrine problem affecting women
of reproductive age and is investigated from many regions of the world. Some reports have …

[HTML][HTML] Consensus on women's health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop …

BCJM Fauser, BC Tarlatzis, RW Rebar, RS Legro… - Fertility and sterility, 2012 - Elsevier
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in females, with
a high prevalence. The etiology of this heterogeneous condition remains obscure, and its …

Molecular & genetic factors contributing to insulin resistance in polycystic ovary syndrome

S Mukherjee, A Maitra - Indian Journal of Medical Research, 2010 - journals.lww.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of unknown
etiology. Insulin resistance is very common and plays a central pathogenic role in PCOS …

Associations of insulin receptor and insulin receptor substrates genetic polymorphisms with polycystic ovary syndrome: A systematic review and meta‐analysis

X Shi, X Xie, Y Jia, S Li - Journal of Obstetrics and Gynaecology …, 2016 - Wiley Online Library
Aim Recently, the roles of insulin receptor (INSR) and insulin receptor substrate (IRS)
polymorphisms in polycystic ovary syndrome (PCOS) have been extensively studied, with …

Genetic markers of polycystic ovary syndrome: emphasis on insulin resistance

N Shaikh, R Dadachanji… - International Journal of …, 2014 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting women of
childbearing age causing not only reproductive but also metabolic anomalies. PCOS women …

Ethnic-specific polycystic ovary syndrome: epidemiology, significance and implications

CN Wijeyaratne, SA Dilini Udayangani… - Expert Review of …, 2013 - Taylor & Francis
Being the most common endocrinopathy of young women, polycystic ovary syndrome has
much variation in its clinical expression based on ancestry. Ethnic differences of the …

Polymorphisms of the insulin receptor and the insulin receptor substrates genes in polycystic ovary syndrome: a Mendelian randomization meta-analysis

A Ioannidis, E Ikonomi, NL Dimou, L Douma… - Molecular genetics and …, 2010 - Elsevier
Polycystic ovary syndrome (PCOS) is a heterogeneous condition with unknown aetiology
which is considered to be the most common endocrine disorder in women of reproductive …

[HTML][HTML] A novel single nucleotide polymorphism of INSR gene for polycystic ovary syndrome

EJ Lee, B Oh, JY Lee, K Kimm, SH Lee, KH Baek - Fertility and sterility, 2008 - Elsevier
OBJECTIVE: To investigate several single nucleotide polymorphisms (SNPs) in the insulin
receptor (INSR) gene that have significant associations with pathogenesis of polycystic …

Association of IRS-1 and IRS-2 genes polymorphisms with polycystic ovary syndrome: a meta-analysis

Y Ruan, J Ma, X Xie - Endocrine journal, 2012 - jstage.jst.go.jp
Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing
210006, China abstract. Insulin resistance (IR) plays an important role in the pathogenesis …