Our brains consist of 80% water, which is continuously shifted between different
compartments and cell types during physiological and pathophysiological processes …

A modern understanding of how cerebral cortical lesions develop after acute brain injury is
based on Aristides Leão's historic discoveries of spreading depression and asphyxial/anoxic …

INTRODUCTION Cerebrospinal fluid (CSF) covers and protects the brain from mechanical
injury. CSF also flows along an interconnected network of perivascular spaces surrounding …

Microglia are the main immune cells of the brain and contribute to common brain diseases.
However, it is unclear how microglia influence neuronal activity and survival in the injured …

Abstract Purpose of Review Delayed cerebral ischemia (DCI) is common after subarachnoid
hemorrhage (SAH) and represents a significant cause of poor functional outcome. DCI was …

Focal brain damage after aneurysmal subarachnoid haemorrhage predominantly results
from intracerebral haemorrhage, and early and delayed cerebral ischaemia. The …

Spreading depolarizations (SD) are waves of abrupt, near-complete breakdown of neuronal
transmembrane ion gradients, are the largest possible pathophysiologic disruption of viable …

Objective To evaluate the association between migraine and incident cardiovascular
disease and cardiovascular mortality in women. Design Prospective cohort study among …

Objective To examine the risks of myocardial infarction, stroke (ischaemic and
haemorrhagic), peripheral artery disease, venous thromboembolism, atrial fibrillation or …

Abstract Recording infraslow brain signals (< 0.1 Hz) with microelectrodes is severely
hampered by current microelectrode materials, primarily due to limitations resulting from …