[HTML][HTML] Therapeutic application of quercetin in aging-related diseases: SIRT1 as a potential mechanism
Z Cui, X Zhao, FK Amevor, X Du, Y Wang, D Li… - Frontiers in …, 2022 - frontiersin.org
Quercetin, a naturally non-toxic flavonoid within the safe dose range with antioxidant, anti-
apoptotic and anti-inflammatory properties, plays an important role in the treatment of aging …
apoptotic and anti-inflammatory properties, plays an important role in the treatment of aging …
[HTML][HTML] Atherosclerosis and inflammation: insights from the theory of general pathological processes
E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …
Apoptosis, necroptosis, and pyroptosis as alternative cell death pathways induced by chemotherapeutic agents?
For decades, common chemotherapeutic drugs have been established to trigger apoptosis,
the preferred immunologically “silent” form of cell death. The primary objective of this review …
the preferred immunologically “silent” form of cell death. The primary objective of this review …
[HTML][HTML] The emerging role of pyroptosis in pediatric cancers: from mechanism to therapy
H Wang, X Zhou, C Li, S Yan, C Feng, J He… - Journal of hematology & …, 2022 - Springer
Pediatric cancers are the driving cause of death for children and adolescents. Due to safety
requirements and considerations, treatment strategies and drugs for pediatric cancers have …
requirements and considerations, treatment strategies and drugs for pediatric cancers have …
Pyroptosis as a double-edged sword: The pathogenic and therapeutic roles in inflammatory diseases and cancers
Z Liu, C Wang, C Lin - Life Sciences, 2023 - Elsevier
Pyroptosis is a programmed cell death mode discovered in recent years. It is caused by
inflammasomes and the perforation of Gasdermin family proteins, and results in the release …
inflammasomes and the perforation of Gasdermin family proteins, and results in the release …
[HTML][HTML] Crosstalk between ferroptosis and chondrocytes in osteoarthritis: a systematic review of in vivo and in vitro studies
Purpose Recent scientific reports have revealed a close association between ferroptosis
and the occurrence and development of osteoarthritis (OA). Nevertheless, the precise …
and the occurrence and development of osteoarthritis (OA). Nevertheless, the precise …
Recent advances of traditional Chinese medicine for the prevention and treatment of atherosclerosis
W Zhi, Y Liu, X Wang, H Zhang - Journal of Ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance Atherosclerosis (AS) is a common systemic disease with
increasing morbidity and mortality worldwide. Traditional Chinese medicine (TCM) with …
increasing morbidity and mortality worldwide. Traditional Chinese medicine (TCM) with …
[HTML][HTML] The initiator of neuroexcitotoxicity and ferroptosis in ischemic stroke: glutamate accumulation
G Fan, M Liu, J Liu, Y Huang - Frontiers in Molecular Neuroscience, 2023 - frontiersin.org
Glutamate plays an important role in excitotoxicity and ferroptosis. Excitotoxicity occurs
through over-stimulation of glutamate receptors, specifically NMDAR, while in the non …
through over-stimulation of glutamate receptors, specifically NMDAR, while in the non …
[HTML][HTML] Endoplasmic reticulum stress-mediated cell death in cardiovascular disease
Y An, X Wang, X Guan, P Yuan, Y Liu, L Wei… - Cell Stress and …, 2024 - Elsevier
The endoplasmic reticulum (ER) plays a vital function in maintaining cellular homeostasis.
Endoplasmic reticulum stress (ERS) can trigger various modes of cell death by activating the …
Endoplasmic reticulum stress (ERS) can trigger various modes of cell death by activating the …
[HTML][HTML] Emerging field: O-GlcNAcylation in ferroptosis
H Zhang, J Zhang, H Dong, Y Kong… - Frontiers in Molecular …, 2023 - frontiersin.org
In 2012, researchers proposed a non-apoptotic, iron-dependent form of cell death caused by
lipid peroxidation called ferroptosis. During the past decade, a comprehensive …
lipid peroxidation called ferroptosis. During the past decade, a comprehensive …