The ups and downs of caloric restriction and fasting: from molecular effects to clinical application
SJ Hofer, D Carmona‐Gutierrez, MI Mueller… - EMBO Molecular …, 2022 - embopress.org
Age‐associated diseases are rising to pandemic proportions, exposing the need for efficient
and low‐cost methods to tackle these maladies at symptomatic, behavioral, metabolic, and …
and low‐cost methods to tackle these maladies at symptomatic, behavioral, metabolic, and …
Impact of intermittent fasting on health and disease processes
Humans in modern societies typically consume food at least three times daily, while
laboratory animals are fed ad libitum. Overconsumption of food with such eating patterns …
laboratory animals are fed ad libitum. Overconsumption of food with such eating patterns …
Intermittent metabolic switching, neuroplasticity and brain health
MP Mattson, K Moehl, N Ghena… - Nature Reviews …, 2018 - nature.com
During evolution, individuals whose brains and bodies functioned well in a fasted state were
successful in acquiring food, enabling their survival and reproduction. With fasting and …
successful in acquiring food, enabling their survival and reproduction. With fasting and …
[HTML][HTML] The effects of intermittent fasting on brain and cognitive function
The importance of diet and the gut-brain axis for brain health and cognitive function is
increasingly acknowledged. Dietary interventions are tested for their potential to prevent …
increasingly acknowledged. Dietary interventions are tested for their potential to prevent …
[HTML][HTML] Brain insulin resistance and hippocampal plasticity: mechanisms and biomarkers of cognitive decline
In the last decade, much attention has been devoted to the effects of nutrient-related signals
on brain development and cognitive functions. A turning point was the discovery that brain …
on brain development and cognitive functions. A turning point was the discovery that brain …
The role of oxidative stress in Parkinson's disease
V Dias, E Junn, MM Mouradian - Journal of Parkinson's …, 2013 - content.iospress.com
Oxidative stress plays an important role in the degeneration of dopaminergic neurons in
Parkinson's disease (PD). Disruptions in the physiologic maintenance of the redox potential …
Parkinson's disease (PD). Disruptions in the physiologic maintenance of the redox potential …
Potential therapeutic uses of BDNF in neurological and psychiatric disorders
AH Nagahara, MH Tuszynski - Nature reviews Drug discovery, 2011 - nature.com
The growth factor brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin-
related kinase receptor type B (TRKB) are actively produced and trafficked in multiple …
related kinase receptor type B (TRKB) are actively produced and trafficked in multiple …
An affective neuroscience model of boosting resilience in adults
G Tabibnia - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
Although research has identified dozens of behavioral and psychosocial strategies for
boosting resilience in adults, little is known about the common underlying pathways. A …
boosting resilience in adults, little is known about the common underlying pathways. A …
[PDF][PDF] Energy intake and exercise as determinants of brain health and vulnerability to injury and disease
MP Mattson - Cell metabolism, 2012 - cell.com
Evolution favored individuals with superior cognitive and physical abilities under conditions
of limited food sources, and brain function can therefore be optimized by intermittent dietary …
of limited food sources, and brain function can therefore be optimized by intermittent dietary …
Brain-derived neurotrophic factor in neurodegenerative diseases
C Zuccato, E Cattaneo - Nature Reviews Neurology, 2009 - nature.com
Abstract Changes in the levels and activities of neurotrophic factors, such as brain-derived
neurotrophic factor (BDNF), have been described in a number of neurodegenerative …
neurotrophic factor (BDNF), have been described in a number of neurodegenerative …