Objectives To investigate the long-term effects of source-specific particle matter (PM) on lung
function, effects of Surfactant Protein A (SP-A) and glutathione S-transferase (GST) genes …

GSTT1 gene plays an important role in detoxification and clearance of reactive oxygen
species (ROS). A null variant in this gene has been demonstrated to confer cancer …

Background Although the impact of early life acetaminophen on asthma risk is still not clear,
potential interactions with glutathione S-transferase (GST) genes due to reduced antioxidant …

Allergic rhinitis as common airway disease has high prevalence in all peoples worldwide. In
allergic diseases, Th2 cells release type 2 cytokines that support the inflammation in …

The glutathione S-transferases (GSTs) are a family of phase II xenobiotic metabolizing
enzymes known to be involved in the detoxification and elimination of reactive oxygen …

Air pollution is a significant health risk factor all over the world. A global study of diseases
showed that air pollution is one of the top ten global health risk factors. Approximately 7 …

The respiratory system is commonly known for being responsible for gaseous exchange.
However, chronic exposure to air born pollution increases each year the number of asthma …

Background Studies have reported gene-by-environment interaction for chronic respiratory
conditions but none on acute illnesses in children. We investigated, longitudinally, whether …

Background GSTT1 encodes the phase II metabolizing enzyme glutathione S-transferase
theta. It is located in a gene cluster with GSTT2 and GSTT2B paralogues on chromosome 22 …

Low birth weight is associated with exposure to air pollution during pregnancy. The purpose
of this study was to evaluate whether null polymorphisms of Glutathione S-transferases …