Targeted therapies and the consequent adoption of “personalized” oncology have achieved
notable successes in some cancers; however, significant problems remain with this …

Throughout the world, cancer is one of the main causes of mortality, threatening the public
health in many countries. As a result, cancer therapy researchers are paying increasing …

Cancer drug resistance is an enormous problem. It is responsible for most relapses in
cancer patients following apparent remission after successful therapy. Understanding …

Multifunctional nanomaterials with the ability to respond to near-infrared (NIR) light
stimulation are vital for the development of highly efficient biomedical nanoplatforms with a …

Epithelial–mesenchymal transition (EMT) programs play essential functions in normal
morphogenesis and organogenesis, including that occurring during mammary gland …

Human cancer cell lines are an integral part of drug discovery practices. However, modeling
the complexity of cancer utilizing these cell lines on standard plastic substrata, does not …

The acquisition of cancer cell resistance to conventional chemotherapeutics is considered
the major driver of treatment failure and disease recurrence in most solid and hematological …

Risk of cancer especially of colon, breast, and pancreas is high in diabetic and obese
patients, with potential involvement of augmented expression of RAGE (receptor for …

Ovarian cancer is the most lethal malignancy among the gynecological cancers, with a 5‐
year survival rate, mainly due to being diagnosed at advanced stages, recurrence and …

Background Doxorubicin is one of the most commonly prescribed and time-tested anticancer
drugs. Although being considered as a first line drug in different types of cancers, the two …