Cancer chemotherapy resistance: Mechanisms and recent breakthrough in targeted drug delivery
F Davodabadi, SF Sajjadi, M Sarhadi… - European Journal of …, 2023 - Elsevier
Conventional chemotherapy, one of the most widely used cancer treatment methods, has
serious side effects, and usually results in cancer treatment failure. Drug resistance is one of …
serious side effects, and usually results in cancer treatment failure. Drug resistance is one of …
[HTML][HTML] Cytokines in cancer drug resistance: Cues to new therapeutic strategies
The development of oncoprotein-targeted anticancer drugs is an invaluable weapon in the
war against cancer. However, cancers do not give up without a fight. They may develop …
war against cancer. However, cancers do not give up without a fight. They may develop …
Dual‐Locking nanoparticles disrupt the PD‐1/PD‐L1 pathway for efficient cancer immunotherapy
The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR‐associated
(Cas) enzyme, Cas13a, holds great promise in cancer treatment due to its potential for …
(Cas) enzyme, Cas13a, holds great promise in cancer treatment due to its potential for …
Wharton jelly-derived mesenchymal stem cell exosomes induce apoptosis and suppress EMT signaling in cervical cancer cells as an effective drug carrier system of …
Mesenchymal stem cells can be obtained and multiplied from various sources and have a
very high capacity to release exosomes. Exosomes are nano-sized extracellular vesicles …
very high capacity to release exosomes. Exosomes are nano-sized extracellular vesicles …
Advances in mesoporous silica-based nanocarriers for co-delivery and combination therapy against cancer
Introduction: Nanocarriers have emerged as a powerful alternative for cancer therapy.
Indeed, they are promising candidates to tackle the acquired resistance of surviving cells …
Indeed, they are promising candidates to tackle the acquired resistance of surviving cells …
Mechanisms of drug resistance in ovarian cancer and associated gene targets
KL Alatise, S Gardner, A Alexander-Bryant - Cancers, 2022 - mdpi.com
Simple Summary When tumors become resistant to chemotherapeutics, alternative
treatment strategies must be explored. Gene targeting provides a personalized and …
treatment strategies must be explored. Gene targeting provides a personalized and …
DNA damage response and resistance of cancer stem cells
E Abad, D Graifer, A Lyakhovich - Cancer Letters, 2020 - Elsevier
The cancer stem cell (CSC) model defines tumors as hierarchically organized entities,
containing a small population of tumorigenic CSC, or tumour-initiating cells, placed at the …
containing a small population of tumorigenic CSC, or tumour-initiating cells, placed at the …
Assessment of anticancer, antimicrobial, antidiabetic, anti-obesity and antioxidant activity of Ocimum Basilicum seeds essential oil from Palestine
Background Many modern pharmaceutical researchers continue to focus on the discovery
and evaluation of natural compounds for possible therapies for obesity, diabetes, infections …
and evaluation of natural compounds for possible therapies for obesity, diabetes, infections …
Novel delivery approaches for cancer therapeutics
AK Mitra, V Agrahari, A Mandal, K Cholkar… - Journal of controlled …, 2015 - Elsevier
Currently, a majority of cancer treatment strategies are based on the removal of tumor mass
mainly by surgery. Chemical and physical treatments such as chemo-and radiotherapies …
mainly by surgery. Chemical and physical treatments such as chemo-and radiotherapies …
Pharmacological targeting of cell cycle, apoptotic and cell adhesion signaling pathways implicated in chemoresistance of cancer cells
Chemotherapeutic drugs target a physiological differentiating feature of cancer cells as they
tend to actively proliferate more than normal cells. They have well-known side-effects …
tend to actively proliferate more than normal cells. They have well-known side-effects …