Plant antimicrobial peptides as potential anticancer agents

JJ Guzmán-Rodríguez… - BioMed research …, 2015 - Wiley Online Library
Antimicrobial peptides (AMPs) are part of the innate immune defense mechanism of many
organisms and are promising candidates to treat infections caused by pathogenic bacteria to …

[HTML][HTML] The current status and future prospects for therapeutic targeting of KEAP1-NRF2 and β-TrCP-NRF2 interactions in cancer chemoresistance

R Srivastava, R Fernández-Ginés, JA Encinar… - Free Radical Biology …, 2022 - Elsevier
Drug resistance is one of the biggest challenges in cancer treatment and limits the potential
to cure patients. In many tumors, sustained activation of the protein NRF2 makes tumor cells …

[HTML][HTML] Drug-loaded polymeric nanoparticles for cancer stem cell targeting

B Li, Q Li, J Mo, H Dai - Frontiers in Pharmacology, 2017 - frontiersin.org
Cancer stem cells (CSCs) have been reported to play critical roles in tumor initiation,
propagation, and regeneration of cancer. Nano-size vehicles are employed to deliver drugs …

[HTML][HTML] Identification of subtypes of anticancer peptides based on sequential features and physicochemical properties

KY Huang, YJ Tseng, HJ Kao, CH Chen, HH Yang… - Scientific reports, 2021 - nature.com
Anticancer peptides (ACPs) are a kind of bioactive peptides which could be used as a novel
type of anticancer drug that has several advantages over chemistry-based drug, including …

[HTML][HTML] Nanotechnology-based combination therapy for overcoming multidrug-resistant cancer

M Zhang, E Liu, Y Cui, Y Huang - Cancer biology & medicine, 2017 - ncbi.nlm.nih.gov
Multidrug resistance (MDR) is a major obstacle to successful cancer treatment and is crucial
to cancer metastasis and relapse. Combination therapy is an effective strategy for …

[HTML][HTML] The promise of Piperine in cancer chemoprevention

S Benayad, H Wahnou, R El Kebbaj, B Liagre, V Sol… - Cancers, 2023 - mdpi.com
Simple Summary With 19.3 million new cancer cases worldwide and nearly 10.0 million
cancer-related deaths cancer is a global health challenge. Cancer is a disease caused by a …

[HTML][HTML] Nutritional Value and Preventive Role of Nigella sativa L. and Its Main Component Thymoquinone in Cancer: An Evidenced-Based Review of Preclinical and …

J Ansary, F Giampieri, TY Forbes-Hernandez, L Regolo… - Molecules, 2021 - mdpi.com
In recent times, scientific attention has been paid to different foods and their bioactive
components for the ability to inhibit the onset and progress of different types of cancer …

The interactions between DNA methylation machinery and long non-coding RNAs in tumor progression and drug resistance

MJ Al-Imam, UAR Hussein, FF Sead, AMA Faqri… - DNA repair, 2023 - Elsevier
DNA methylation is one of the main epigenetic mechanisms in cancer development and
progression. Aberrant DNA methylation of CpG islands within promoter regions contributes …

Metabolomics applications in precision medicine: an oncological perspective

L Puchades-Carrasco… - Current topics in …, 2017 - ingentaconnect.com
Nowadays, cancer therapy remains limited by the conventional one-size-fits-all approach. In
this context, treatment decisions are based on the clinical stage of disease but fail to …

[HTML][HTML] HOXA9 transcription factor is a double-edged sword: from development to cancer progression

US Shenoy, D Adiga, F Alhedyan… - Cancer and Metastasis …, 2024 - Springer
The HOXA9 transcription factor serves as a molecular orchestrator in cancer stemness,
epithelial-mesenchymal transition (EMT), metastasis, and generation of the tumor …