Chemotherapy is one of the main methods for cancer treatment. However, despite many
advances in the design of anticancer drugs, their efficiency is limited due to their high toxicity …

Small molecules that deter the functions of DNA damage response machinery are
postulated to be useful for enhancing the DNA damaging effects of chemotherapy or ionizing …

Highlights•STAT3 is critically involved in the regulation of chemoresistance.•STAT3
modulates cancer stemness through the EMT program and ABC transporters.•A STAT3 …

Exosomes affect the initiation and progression of cancers. In the tumor microenvironment,
not only cancer cells, but also fibroblasts and immunocytes secrete exosomes. Exosomes …

Historically, the link between chronic inflammation and cancer has long been speculated.
Only more recently, pre-clinical and epidemiologic data as well as clinical evidence all point …

Triple-negative breast cancer (TNBC) remains a serious health issue for women worldwide
due to the high malignancy and invasiveness. Despite combination therapies of TNBC have …

Coriolus versicolor (CV) is a common species from the Polyporaceae family that has been
used in traditional Chinese herbal medicine for over 2000 years. Among well-described and …

The microtubule (MT) cytoskeleton provides the architecture that governs intracellular
organization and the regulated motion of macromolecules through the crowded cytoplasm …

Multidrug resistance (MDR) and adverse side effects are the major challenges facing cancer
chemotherapy. Here, pH/protease dually responsive, sericin‐coated mesoporous silica …

DNA damaging agents are most common in chemotherapeutic molecules that act against
cancer. However, cancer cells possess inherent biological features to overcome DNA …