Botanicals in postmenopausal osteoporosis

W Słupski, P Jawień, B Nowak - Nutrients, 2021 - mdpi.com
Osteoporosis is a systemic bone disease characterized by reduced bone mass and the
deterioration of bone microarchitecture leading to bone fragility and an increased risk of …

The role of inflammation in cadmium nephrotoxicity: NF-κB comes into view

EHM Hassanein, WR Mohamed, OS Ahmed… - Life Sciences, 2022 - Elsevier
Kidney diseases are major health problem and understanding the underlined mechanisms
that lead to kidney diseases are critical research points with a marked potential impact on …

The synergistic effects of polyphenols and intestinal microbiota on osteoporosis

K Wang, S Hu - Frontiers in Immunology, 2023 - frontiersin.org
Osteoporosis is a common metabolic disease in middle-aged and elderly people. It is
characterized by a reduction in bone mass, compromised bone microstructure, heightened …

[HTML][HTML] Advances in the pharmacological study of Chinese herbal medicine to alleviate diabetic nephropathy by improving mitochondrial oxidative stress

M Chen, Y Chen, W Zhu, X Yan, J Xiao, P Zhang… - Biomedicine & …, 2023 - Elsevier
Diabetic nephropathy (DN) is one of the serious complications of diabetes mellitus, primarily
arising from type 2 diabetes (T2DM), and can progress to chronic kidney disease (CKD) and …

Synthesis, characterization, and in vitro anti-tumor activity studies of the hyaluronic acid-mangiferin-methotrexate nanodrug targeted delivery system

H Wang, W Shao, X Lu, C Gao, L Fang, X Yang… - International Journal of …, 2023 - Elsevier
In this study, to increase the accumulation of MTX in the tumor site and reduce the toxicity to
normal tissues by MA, a novel nano-drug delivery system comprised of hyaluronic acid (HA) …

Non-flavonoid polyphenols in osteoporosis: Preclinical evidence

D Bellavia, F Caradonna, E Dimarco, V Costa… - Trends in Endocrinology …, 2021 - cell.com
The development of progressive osteopenia and osteoporosis (OP) is due to the imbalance
between bone resorption and bone formation, determining a lower bone resistance, major …

A review of antidiabetic active thiosugar sulfoniums, salacinol and neokotalanol, from plants of the genus Salacia

T Morikawa, K Ninomiya, G Tanabe, H Matsuda… - Journal of natural …, 2021 - Springer
During our studies characterizing functional substances from food resources for the
prevention and treatment of lifestyle-related diseases, we isolated the active constituents …

Development of mangiferin loaded chitosan-silica hybrid scaffolds: Physicochemical and bioactivity characterization

S Demeyer, A Athipornchai, P Pabunrueang… - Carbohydrate …, 2021 - Elsevier
Abstract Development of hybrid materials with molecular structure of organic-inorganic co-
network is a promising method to enhance the stability and mechanical properties of …

Er-xian decoction drug-containing serum promotes Mc3t3-e1 cell proliferation and osteogenic differentiation via regulating BK channel

MS Ren, HH Xie, Y Ding, ZH Li, B Liu - Journal of Ethnopharmacology, 2023 - Elsevier
Abstract Ethnopharmacological relevance Er-xian Decoction (EXD) is a well-known
prescription widely used to prevent and treat climacteric syndrome and osteoporosis in …

Identification of novel cannabinoid CB2 receptor agonists from botanical compounds and preliminary evaluation of their anti-osteoporotic effects

SJ Hu, G Cheng, H Zhou, Q Zhang, QL Zhang, Y Wang… - Molecules, 2022 - mdpi.com
As cannabinoid CB2 receptors (CB2R) possess various pharmacological effects—including
anti-epilepsy, analgesia, anti-inflammation, anti-fibrosis, and regulation of bone metabolism …