The biological efficacy of natural products against acute and chronic inflammatory diseases in the oral region

T Ara, S Nakatani, K Kobata, N Sogawa, C Sogawa - Medicines, 2018 - mdpi.com
The oral inflammatory diseases are divided into two types: acute and chronic inflammatory
diseases. In this review, we summarize the biological efficacy of herbal medicine, natural …

CpG ODN/Mangiferin Dual Delivery through Calcium Alginate Hydrogels Inhibits Immune-Mediated Osteoclastogenesis and Promotes Alveolar Bone Regeneration in …

Y Gu, Y Hu, S Huang, S Ruiz, T Kawai, Y Bai, X Han - Biology, 2023 - mdpi.com
Simple Summary The immune system plays an important role in the skeletal system during
bone repair and regeneration, especially in the oral environment with its constant host …

Effects of urolithin A on osteoclast differentiation induced by receptor activator of nuclear factor-κB ligand via bone morphogenic protein 2

Z Wang, G Qi, Z Li, X Cui, S Guo, Y Zhang, P Cai… - …, 2022 - Taylor & Francis
Urolithin A (UA) is an intestinal microbial metabolite derived from ellagitannins and a
promising agent for treating osteoarthritis. However, its effects on osteoporosis are unclear …

Effects of Mangiferin on LPS-Induced Inflammation and SARS-CoV-2 Viral Adsorption in Human Lung Cells

M Spampinato, G Carota, G Sferrazzo, V Fuochi… - Pharmaceutics, 2022 - mdpi.com
The growing interest in natural bioactive molecules, as an approach to many pathological
contexts, is widely justified by the necessity to overcome the disadvantageous benefit–risk …

Mangiferin promotes osteogenic differentiation and alleviates osteoporosis in the ovariectomized mouse via the AXL/ERK5 pathway

J He, X Wang, D Zhao, B Geng, Y Xia - Frontiers in Pharmacology, 2022 - frontiersin.org
Mangiferin is a xanthone glucoside extracted from multiple plants, which has been shown to
inhibit bone resorption and alleviate osteoporosis. However, the effect of purified Mangiferin …

Optimizing nutrient media conditions for continuous production of shoot biomass enriched in major medicinal constituents, amarogentin and mangiferin of endangered …

R Gupta, H Sood - Vegetos, 2023 - Springer
Biosynthesis and accumulation of Amarogentin and Mangiferin from shoot culture of
endangered herb Swertia chirayita helped in rescuing its natural population along with …

Cyclopia extracts act as selective estrogen receptor subtype downregulators in estrogen receptor positive breast cancer cell lines: Comparison to standard of care …

FR Olayoku, NJD Verhoog, A Louw - Frontiers in Pharmacology, 2023 - frontiersin.org
Breast cancer is the most diagnosed type of cancer amongst women in economically
developing countries and globally. Most breast cancers express estrogen receptor alpha …

Mangiferin: A natural bioactive immunomodulating glucosylxanthone with potential against cancer and rheumatoid arthritis

AS Akkewar, KMA Mishra… - Journal of Biochemical and …, 2024 - Wiley Online Library
Mangiferin is a naturally occurring glucosylxanthone that has shown promising
immunomodulatory effects. It is generally isolated from the leaves, peels, bark, and kernels …

[HTML][HTML] Ethanolic extract of Pyrrosia lingua (Thunb.) Farw. ameliorates OVX-induced bone loss and RANKL-induced osteoclastogenesis

SA Jang, YH Hwang, H Yang, JA Ryuk, DR Gu… - Biomedicine & …, 2022 - Elsevier
Abstract Pyrrosia lingua (Thunb.) Farw is a common plant that has been widely used as a
traditional herbal medicine in China and Korea to treat patients suffering from pain, vaginal …

Farnesoid X receptor agonist attenuates subchondral bone osteoclast fusion and osteochondral pathologies of osteoarthritis via suppressing JNK1/2/NFATc1 pathway

W Hu, C Cai, Y Li, F Kang, T Chu, S Dong - The FASEB Journal, 2022 - Wiley Online Library
Osteoarthritis (OA) is a prevalent degenerative disease of the joint, featured by articular
cartilage destruction and subchondral bone marrow lesions. Articular cartilage and …