Ischaemic heart disease and the heart failure that often results, remain the leading causes of
death and disability in Europe and worldwide. As such, in order to prevent heart failure and …

The mortality from acute myocardial infarction (AMI) remains significant, and the prevalence
of post-myocardial infarction heart failure is increasing. Therefore, cardioprotection beyond …

Aims Remote ischaemic conditioning (RIC) and postconditioning (PostC) are both potent
activators of innate protection against ischaemia–reperfusion injury and have demonstrated …

Primary percutaneous coronary intervention (PCI) is the best available reperfusion strategy
for acute ST-segment elevation myocardial infarction (STEMI), with nearly 95% of occluded …

Abstract The Hatter Cardiovascular Institute biennial workshop, originally scheduled for April
2020 but postponed for 2 years due to the Covid pandemic, was organised to debate and …

In the 30 years since the original description of ischaemic preconditioning, understanding of
the pathophysiology of ischaemia/reperfusion injury and concepts of cardioprotection have …

Despite decades of formidable exploration, multi-organ ischemia-reperfusion injury (IRI)
encountered, particularly amongst elderly patients with clinical scenarios, such as age …

Background Remote ischemic conditioning (RIC) is a noninvasive therapeutic strategy that
uses brief cycles of blood pressure cuff inflation and deflation to protect the myocardium …

Ischemia–reperfusion injury (IRI) is a major, but potentially preventable contributor to the
final tissue damage after an acute myocardial infarction. Many therapies have demonstrated …

Early coronary artery reperfusion improves outcomes for patients with ST-segment elevation
myocardial infarction (STEMI), but morbidity and mortality after STEMI remain unacceptably …