Particles in Exhaled Air (PExA): Clinical Uses and Future Implications

T Roe, S Silveira, Z Luo, EL Osborne… - Diagnostics, 2024 - mdpi.com
Access to distal airway samples to assess respiratory diseases is not straightforward and
requires invasive procedures such as bronchoscopy and bronchoalveolar lavage. The …

Comparison of particles in exhaled air and multiple breath washout for assessment of small airway function in children with cystic fibrosis

AM Zwitserloot, FA Verhoog… - Pediatric …, 2024 - Wiley Online Library
Background The introduction of modulator therapy for cystic fibrosis (CF) has led to an
increased interest in the detection of small airway disease (SAD) as sensitive marker of …

Exhaled particles

K Schwarz, O Holz, JM Hohlfeld - Breathborne Biomarkers and the Human …, 2020 - Elsevier
Particles in exhaled breath are most likely generated when collapsed small airways reopen
during inhalation, a phenomenon sometimes referred to as “surface film disruption” or “fluid …