[HTML][HTML] Hypothyroidism in context: where we've been and where we're going

L Chiovato, F Magri, A Carlé - Advances in therapy, 2019 - Springer
Hypothyroidism affects up to 5% of the general population, with a further estimated 5% being
undiagnosed. Over 99% of affected patients suffer from primary hypothyroidism. Worldwide …

[HTML][HTML] Hypothyroidism in the older population

O Leng, S Razvi - Thyroid research, 2019 - Springer
Background Both overt hypothyroidism as well as minor elevations of serum thyrotropin
(TSH) levels associated with thyroid hormones within their respective reference ranges …

Thyroid hormone therapy for older adults with subclinical hypothyroidism

DJ Stott, N Rodondi, PM Kearney, I Ford… - … England Journal of …, 2017 - Mass Medical Soc
Background The use of levothyroxine to treat subclinical hypothyroidism is controversial. We
aimed to determine whether levothyroxine provided clinical benefits in older persons with …

Efficacy and safety of ashwagandha root extract in subclinical hypothyroid patients: a double-blind, randomized placebo-controlled trial

AK Sharma, I Basu, S Singh - The Journal of Alternative and …, 2018 - liebertpub.com
Background: Subclinical hypothyroidism, a thyroid disorder without obvious symptoms of
thyroid deficiency, occurs in 3%–8% of the global population. Ashwagandha [Withania …

Subclinical hypothyroidism, outcomes and management guidelines: a narrative review and update of recent literature

B Urgatz, S Razvi - Current Medical Research and Opinion, 2023 - Taylor & Francis
Subclinical hypothyroidism (SCH) is diagnosed when serum thyroid stimulation hormone
(thyrotropin; TSH) levels are above the reference range, accompanied by levels of free …

Prevalence and clinical correlates of subclinical hypothyroidism in first-episode drug-naive patients with major depressive disorder in a large sample of Chinese

XE Lang, X Hou, F Shangguan, XY Zhang - Journal of affective disorders, 2020 - Elsevier
Background The coexistence of subclinical hypothyroidism (SCH) and depression has been
intensively examined in the patients receiving thyroxine or antidepressant treatment. This …

[HTML][HTML] The impact of levothyroxine on cardiac function in older adults with mild subclinical hypothyroidism: a randomized clinical trial

B Gencer, E Moutzouri, MR Blum, M Feller… - The American journal of …, 2020 - Elsevier
Background Subclinical hypothyroidism has been associated with heart failure, but only
small trials assessed whether treatment with levothyroxine has an impact on cardiac …

Relationship between subclinical thyroid dysfunction and the risk of cardiovascular outcomes: a systematic review and meta‐analysis of prospective cohort studies

J Sun, L Yao, Y Fang, R Yang, Y Chen… - International journal …, 2017 - Wiley Online Library
Background. Evidence on the association between subclinical thyroid dysfunction and the
risk of cardiovascular outcomes are conflicting. Methods and Results. PubMed, EMbase …

[HTML][HTML] Assay of thyroid hormones and related substances

CA Spencer - 2015 - europepmc.org
This chapter reviews how improvements in sensitivity and specificity of thyroid function tests
[total and free thyroid hormones, TSH, thyroid autoantibodies (TRAb, TPOAb and TgAb) and …

The prevalence and clinical correlates of suicide attempts in comorbid subclinical hypothyroidism in patients with never-treated major depressive disorder in China

F Shangguan, Z Chen, L Feng, J Lu… - Journal of affective …, 2022 - Elsevier
Background Previous studies have emphasized the possible association between
subclinical hypothyroidism (SCH) and major depressive disorder (MDD). This study aimed to …