[HTML][HTML] Role of the NLRP3 inflammasome in cancer

M Moossavi, N Parsamanesh, A Bahrami, SL Atkin… - Molecular cancer, 2018 - Springer
Inflammasomes are large intracellular multi-protein signalling complexes that are formed in
the cytosolic compartment as an inflammatory immune response to endogenous danger …

The cost of inflammatory bowel disease in high-income settings: a Lancet Gastroenterology & Hepatology Commission

J Burisch, M Zhao, S Odes, P De Cruz… - The Lancet …, 2023 - thelancet.com
The cost of caring for patients with inflammatory bowel disease (IBD) continues to increase
worldwide. The cause is not only a steady increase in the prevalence of Crohn's disease …

Visceral Adipose Tissue Derived Exosomes Exacerbate Colitis Severity via Pro-inflammatory MiRNAs in High Fat Diet Fed Mice

M Wei, X Gao, L Liu, Z Li, Z Wan, Y Dong, X Chen… - ACS …, 2020 - ACS Publications
A pioneering epidemic study has revealed a strong association between obesity and the risk
of colitis. In this study, a high fat diet was found to significantly aggravate colitis induced by …

Systematic review and meta-analysis: short-chain fatty acid characterization in patients with inflammatory bowel disease

X Zhuang, T Li, M Li, S Huang, Y Qiu… - Inflammatory bowel …, 2019 - academic.oup.com
Background Alterations in gut microbiota and short-chain fatty acids (SCFAs) have been
reported in inflammatory bowel disease (IBD), but the results are conflicting. The aim of this …

Hesperetin ameliorates DSS-induced colitis by maintaining the epithelial barrier via blocking RIPK3/MLKL necroptosis signaling

J Zhang, H Lei, X Hu, W Dong - European Journal of Pharmacology, 2020 - Elsevier
Hesperetin, a flavonoid from citrus fruits, possess various pharmacological properties,
including anti-inflammatory, anti-oxidative, anti-tumor potentials. However, the role and its …

Redefining the IBDs using genome-scale molecular phenotyping

TS Furey, P Sethupathy, SZ Sheikh - Nature reviews Gastroenterology & …, 2019 - nature.com
Abstract The IBDs, Crohn's disease and ulcerative colitis, are chronic inflammatory
conditions of the gastrointestinal tract resulting from an aberrant immune response to enteric …

[HTML][HTML] NLRP3 inflammasome-induced pyroptosis in digestive system tumors

J Wen, B Xuan, Y Liu, L Wang, L He, X Meng… - Frontiers in …, 2023 - frontiersin.org
Programmed cell death (PCD) refers to cell death in a manner that depends on specific
genes encoding signals or activities. PCD includes apoptosis, pyroptosis, autophagy and …

Digital health technologies for remote monitoring and management of inflammatory bowel disease: a systematic review

NH Nguyen, I Martinez, A Atreja… - Official journal of the …, 2022 - journals.lww.com
METHODS: Through a systematic review of multiple databases through August 31, 2020, we
identified randomized controlled trials in patients with IBD comparing digital health …

Trends in US health care spending on inflammatory bowel diseases, 1996-2016

S Singh, AS Qian, NH Nguyen, SKM Ho… - Inflammatory Bowel …, 2022 - academic.oup.com
Background Inflammatory bowel diseases (IBD) are rising in prevalence and are associated
with high health care costs. We estimated trends in US health care spending in patients with …

Temporal trends of inflammatory bowel disease burden in China from 1990 to 2030 with comparisons to Japan, South Korea, the European Union, the United States of …

T Ma, M Wan, G Liu, X Zuo, X Yang… - Clinical epidemiology, 2023 - Taylor & Francis
Purpose To identify and predict the epidemiological burden and trends of inflammatory
bowel disease (IBD) in China and compare them globally. Methods We collected incidence …