Multifunctional nanotheranostics for near infrared optical imaging-guided treatment of brain tumors

L Zhang, Y Liu, H Huang, H Xie, B Zhang, W Xia… - Advanced drug delivery …, 2022 - Elsevier
Malignant brain tumors, a heterogeneous group of primary and metastatic neoplasms in the
central nervous system (CNS), are notorious for their highly invasive and devastating …

Progress in polymeric micelles for drug delivery applications

S Kotta, HM Aldawsari, SM Badr-Eldin, AB Nair, K Yt - Pharmaceutics, 2022 - mdpi.com
Polymeric micelles (PMs) have made significant progress in drug delivery applications. A
robust core–shell structure, kinetic stability and the inherent ability to solubilize hydrophobic …

Synchronous disintegration of ferroptosis defense axis via engineered exosome‐conjugated magnetic nanoparticles for glioblastoma therapy

B Li, X Chen, W Qiu, R Zhao, J Duan… - Advanced …, 2022 - Wiley Online Library
Glioblastoma (GBM) is one of the most fatal central nervous system tumors and lacks
effective or sufficient therapies. Ferroptosis is a newly discovered method of programmed …

Glioma diagnosis and therapy: current challenges and nanomaterial-based solutions

T Li, J Li, Z Chen, S Zhang, S Li, S Wageh… - Journal of controlled …, 2022 - Elsevier
Glioma is often referred to as one of the most dreadful central nervous system (CNS)-specific
tumors with rapidly-proliferating cancerous glial cells, accounting for nearly half of the brain …

Stimulus-responsive self-assembled prodrugs in cancer therapy

X Dong, RK Brahma, C Fang, SQ Yao - Chemical science, 2022 - pubs.rsc.org
Small-molecule prodrugs have become the main toolbox to improve the unfavorable
physicochemical properties of potential therapeutic compounds in contemporary anti-cancer …

Nanomaterials for photothermal and photodynamic cancer therapy

B Nasseri, E Alizadeh, F Bani, S Davaran… - Applied Physics …, 2022 - pubs.aip.org
In recent years, the role of optically sensitive nanomaterials has become powerful moieties
in therapeutic techniques and has become particularly emphasized. Currently, by the …

Nanoparticulation of prodrug into medicines for cancer therapy

Y Zhang, H Cui, R Zhang, H Zhang… - Advanced …, 2021 - Wiley Online Library
This article provides a broad spectrum about the nanoprodrug fabrication advances co‐
driven by prodrug and nanotechnology development to potentiate cancer treatment. The …

Carrier-free nanodrugs for safe and effective cancer treatment

S Karaosmanoglu, M Zhou, B Shi, X Zhang… - Journal of Controlled …, 2021 - Elsevier
Clinical applications of many anti-cancer drugs are restricted due to their hydrophobic
nature, requiring use of harmful organic solvents for administration, and poor selectivity and …

Engineering of cascade-responsive nanoplatform to inhibit lactate efflux for enhanced tumor chemo-immunotherapy

K Li, C Lin, Y He, L Lu, K Xu, B Tao, Z Xia, R Zeng… - ACS …, 2020 - ACS Publications
As an increased product of high-rate aerobic glycolysis in tumors, lactate could regulate the
immunosuppressive tumor microenvironment (TME). A PEG-CDM surface modified, GSH …

Recent advances in colorimetry/fluorimetry-based dual-modal sensing technologies

Y Zhou, X Huang, X Hu, W Tong, Y Leng… - Biosensors and …, 2021 - Elsevier
Tailored to the increasing demands for sensing technologies, the fabrication of dual-modal
sensing technologies through combining two signal transduction channels into one method …