Agent-based modeling in cancer biomedicine: applications and tools for calibration and validation

N Cogno, C Axenie, R Bauer… - Cancer Biology & …, 2024 - Taylor & Francis
Computational models are not just appealing because they can simulate and predict the
development of biological phenomena across multiple spatial and temporal scales, but also …

Simpful: a user-friendly python library for fuzzy logic

S Spolaor, C Fuchs, P Cazzaniga, U Kaymak… - International Journal of …, 2020 - Springer
Many researchers have used fuzzy set theory and fuzzy logic in a variety of applications
related to computer science and engineering, given the capability of fuzzy inference systems …

State-of-the-art development of complex systems and their simulation methods

Y Tang, L Li, X Liu - Complex system modeling and simulation, 2021 - ieeexplore.ieee.org
The research on complex systems is different from that on general systems because the
former must consider self-organization, emergence, uncertainty, predetermination, and …

Ten quick tips for fuzzy logic modeling of biomedical systems

D Chicco, S Spolaor, MS Nobile - PLoS Computational Biology, 2023 - journals.plos.org
Fuzzy logic is useful tool to describe and represent biological or medical scenarios, where
often states and outcomes are not only completely true or completely false, but rather …

pyFUME: a Python package for fuzzy model estimation

C Fuchs, S Spolaor, MS Nobile… - 2020 IEEE international …, 2020 - ieeexplore.ieee.org
Living in the era of" data deluge" demands for an increase in the application and
development of machine learning methods, both in basic and applied research. Among …

Takagi–sugeno fuzzy regression trees with application to complex industrial modeling

H Xia, J Tang, W Yu, C Cui… - IEEE Transactions on …, 2022 - ieeexplore.ieee.org
Fuzzy decision trees (FDTs) is one of the considerably excellent methods. Most of the
existing FDTs' methods are oriented to classification tasks. Applying FDTs to regression …

Selection of minimum rules from a fuzzy TSK model using a PSO–FCM combination

L Brikh, O Guenounou, T Bakir - Journal of Control, Automation and …, 2023 - Springer
This work proposes an efficient and promising method for linear and nonlinear dynamic
systems modeling. Unlike previous methods, we combine Fuzzy C-Means (FCM) and …

Fuzzy modeling and global optimization to predict novel therapeutic targets in cancer cells

MS Nobile, G Votta, R Palorini, S Spolaor… - …, 2020 - academic.oup.com
Motivation The elucidation of dysfunctional cellular processes that can induce the onset of a
disease is a challenging issue from both the experimental and computational perspectives …

Multiagent-based modeling and simulation of a coal multimodal transport system

Y Yang, Q Zhou, K Chen - IEEE Access, 2022 - ieeexplore.ieee.org
With the change in coal supply and demand, the dynamics of multiple transit nodes and the
connection between different transportation modes make the Coal Multimodal …

Accelerated global sensitivity analysis of genome-wide constraint-based metabolic models

MS Nobile, V Coelho, D Pescini, C Damiani - BMC bioinformatics, 2021 - Springer
Background Genome-wide reconstructions of metabolism opened the way to thorough
investigations of cell metabolism for health care and industrial purposes. However, the …