[HTML][HTML] Financial burden of tuberculosis diagnosis and treatment for patients in Ethiopia: a systematic review and meta-analysis

DG Assefa, ZG Dememew, ED Zeleke, T Manyazewal… - BMC Public Health, 2024 - Springer
Background Despite the diagnosis and treatment of tuberculosis (TB) given free of charge in
many high-burden countries, the costs that patients face in the cascade of care remain a …

[HTML][HTML] Financial hardship among patients suffering from neglected tropical diseases: A systematic review and meta-analysis of global literature

C Patikorn, JY Cho, J Higashi, XX Huang… - PLOS Neglected …, 2024 - journals.plos.org
Introduction Neglected tropical diseases (NTDs) mainly affect underprivileged populations,
potentially resulting in catastrophic health spending (CHS) and impoverishment from out-of …

Effect of digital medication event reminder and monitor-observed therapy vs standard directly observed therapy on health-related quality of life and catastrophic costs …

T Manyazewal, Y Woldeamanuel, A Fekadu… - JAMA Network …, 2022 - jamanetwork.com
Importance Little is known about whether digital adherence technologies are economical for
patients with tuberculosis (TB) in resource-constrained settings. Objective To test the …

[HTML][HTML] ClpC2 protects mycobacteria against a natural antibiotic targeting ClpC1-dependent protein degradation

G Taylor, H Cui, J Leodolter, C Giese… - Communications …, 2023 - nature.com
Mycobacterium tuberculosis Clp proteases are targeted by several antitubercular
compounds, including cyclomarin A (CymA). CymA exerts its toxicity by binding to AAA+ …

The potential impact of novel tuberculosis vaccines on health equity and financial protection in low-income and middle-income countries

A Portnoy, RA Clark, CK Weerasuriya… - BMJ global …, 2023 - gh.bmj.com
Introduction One in two patients developing tuberculosis (TB) in low-income and middle-
income countries (LMICs) faces catastrophic household costs. We assessed the potential …

[HTML][HTML] Global, regional, and national age-specific progress towards the 2020 milestones of the WHO End TB Strategy: a systematic analysis for the Global Burden of …

JR Ledesma, J Ma, M Zhang, AVL Basting… - The Lancet Infectious …, 2024 - thelancet.com
Background Global evaluations of the progress towards the WHO End TB Strategy 2020
interim milestones on mortality (35% reduction) and incidence (20% reduction) have not …

[HTML][HTML] Survey to measure the quality of life of patients with tuberculosis in Alexandria, Egypt: a cross-sectional study

EA Hammouda, WF Gobran, RM Tawfeek… - BMC Health Services …, 2023 - Springer
Background Assessment of quality of life (QoL) in patients with tuberculosis (TB) may
improve healthcare providers' understanding of the disease burden. This study aimed to …

[HTML][HTML] Catastrophic costs among tuberculosis-affected households in Egypt: Magnitude, cost drivers, and coping strategies

RM Ghazy, M Sallam, R Ashmawy… - International Journal of …, 2023 - mdpi.com
Despite national programs covering the cost of treatment for tuberculosis (TB) in many
countries, TB patients still face substantial costs. The end TB strategy, set by the World …

[HTML][HTML] Economic burden of multidrug-resistant tuberculosis on patients and households: a global systematic review and meta-analysis

TY Akalu, ACA Clements, HF Wolde, KA Alene - Scientific Reports, 2023 - nature.com
Multidrug-resistant tuberculosis (MDR-TB) is a major health threat worldwide, causing a
significant economic burden to patients and their families. Due to the longer duration of …

[HTML][HTML] Understanding the contribution of metabolism to Mycobacterium tuberculosis drug tolerance

AN Samuels, ER Wang, GA Harrison… - Frontiers in cellular …, 2022 - frontiersin.org
Treatment of Mycobacterium tuberculosis (Mtb) infections is particularly arduous. One
challenge to effectively treating tuberculosis is that drug efficacy in vivo often fails to match …