CXCL10 chemokine: a critical player in RNA and DNA viral infections

NM Elemam, IM Talaat, AA Maghazachi - Viruses, 2022 - mdpi.com
Chemokines constitute a group of small, secreted proteins that regulate leukocyte migration
and contribute to their activation. Chemokines are crucial inflammatory mediators that play a …

Innate and adaptive immunity during SARS-CoV-2 infection: biomolecular cellular markers and mechanisms

B Brown, V Ojha, I Fricke, SA Al-Sheboul, C Imarogbe… - Vaccines, 2023 - mdpi.com
The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense single-
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

A comparative study of the plasma chemokine profile in COVID-19 patients infected with different SARS-CoV-2 variants

ZR Korobova, NA Arsentieva, NE Liubimova… - International Journal of …, 2022 - mdpi.com
Background. Infection caused by SARS-CoV-2 mostly affects the upper and lower
respiratory tracts and causes symptoms ranging from the common cold to pneumonia with …

Immunological misfiring and sex differences/similarities in early COVID-19 studies: missed opportunities of making a real IMPACT

A Bhargava, JD Knapp - Cells, 2023 - mdpi.com
COVID-19-associated intensive care unit (ICU) admissions were recognized as critical
health issues that contributed to morbidity and mortality in SARS-CoV-2-infected patients …

The glycosaminoglycan-binding chemokine fragment CXCL9 (74–103) reduces inflammation and tissue damage in mouse models of coronavirus infection

VLS Oliveira, CM Queiroz-Junior… - Frontiers in …, 2024 - frontiersin.org
Introduction Pulmonary diseases represent a significant burden to patients and the
healthcare system and are one of the leading causes of mortality worldwide. Particularly, the …

Brain transcriptomics reveal the activation of neuroinflammation pathways during acute Orientia tsutsugamushi infection in mice

Y Liang, Aditi, F Onyoni, H Wang, C Gonzales… - Frontiers in …, 2023 - frontiersin.org
Scrub typhus, an acute febrile illness caused by Orientia tsutsugamushi (Ot), is prevalent in
endemic areas with one million new cases annually. Clinical observations suggest central …

[HTML][HTML] Importance of IP-10 as a biomarker of host immune response: Critical perspective as a target for biosensing

S Madhurantakam, ZJ Lee, A Naqvi… - Current Research in …, 2023 - Elsevier
While the exploration into biomolecules for diagnostic and prognostic devices continues to
develop, many molecules continue to be examined for individual diseases or treatments …

Cross protection to SARS-CoV-2 variants in hamsters with naturally-acquired immunity

S Beitari, D Duque, J Bavananthasivam, M Hewitt… - Virology Journal, 2023 - Springer
Since SARS-CoV-2 was first reported in late 2019, multiple variations of the original virus
have emerged. Each variant harbors accumulations of mutations, particularly within the …

Distinct cytokine profiles in severe COVID-19 and non-alcoholic fatty liver disease

N Papic, L Samadan, N Vrsaljko, L Radmanic, K Jelicic… - Life, 2022 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is identified as a risk factor for developing severe
COVID-19. While NAFLD is associated with chronic low-grade inflammation, mechanisms …

In vitro and in vivo effects of Pelargonium sidoides DC. root extract EPs® 7630 and selected constituents against SARS-CoV-2 B.1, Delta AY.4/AY.117 and Omicron …

J Emanuel, J Papies, C Galander, JM Adler… - Frontiers in …, 2023 - frontiersin.org
The occurrence of immune-evasive SARS-CoV-2 strains emphasizes the importance to
search for broad-acting antiviral compounds. Our previous in vitro study showed that …