Sirt3 deficiency accelerates ovarian senescence without affecting spermatogenesis in aging mice
J Zhu, Q Yang, H Li, Y Wang, Y Jiang, H Wang… - Free Radical Biology …, 2022 - Elsevier
Abstract Sirtuin-3 (SIRT3), the main deacetylase in the mitochondria, maintains cellular
energy metabolism and redox balance by deacetylating mitochondrial proteins in a NAD+ …
energy metabolism and redox balance by deacetylating mitochondrial proteins in a NAD+ …
Stem cell-based therapeutic strategies for premature ovarian insufficiency and infertility: a focus on aging
Reproductive aging is on the rise globally and inseparable from the entire aging process. An
extreme form of reproductive aging is premature ovarian insufficiency (POI), which to date …
extreme form of reproductive aging is premature ovarian insufficiency (POI), which to date …
RAB7 activity is required for the regulation of mitophagy in oocyte meiosis and oocyte quality control during ovarian aging
X Jin, K Wang, L Wang, W Liu, C Zhang, Y Qiu, W Liu… - Autophagy, 2022 - Taylor & Francis
There is increasing evidence that mitophagy, a specialized form of autophagy to degrade
and clear long-lived or damaged mitochondria, is impaired in aging and age-related …
and clear long-lived or damaged mitochondria, is impaired in aging and age-related …
Control of mitochondrial integrity influences oocyte quality during reproductive aging
SA Khan, L Reed, WB Schoolcraft… - Molecular Human …, 2023 - academic.oup.com
Reduced quality in oocytes from women of advanced maternal age (AMA) is associated with
dysfunctional mitochondria. The objective of this study was to investigate the mechanisms …
dysfunctional mitochondria. The objective of this study was to investigate the mechanisms …
[HTML][HTML] Daphnia as a model organism to probe biological responses to nanomaterials—from individual to population effects via adverse outcome pathways
The importance of the cladoceran Daphnia as a model organism for ecotoxicity testing has
been well-established since the 1980s when it was standardised for regulatory testing of …
been well-established since the 1980s when it was standardised for regulatory testing of …
Does coenzyme Q10 supplementation improve fertility outcomes in women undergoing assisted reproductive technology procedures? A systematic review and meta …
P Florou, P Anagnostis, P Theocharis… - Journal of assisted …, 2020 - Springer
Objective Increased oxidative stress has been identified as a pathogenetic mechanism in
female infertility. However, the effect of specific antioxidants, such as coenzyme Q 10 (CoQ …
female infertility. However, the effect of specific antioxidants, such as coenzyme Q 10 (CoQ …
[HTML][HTML] Global research trends on infertility and psychology from the past two decades: a bibliometric and visualized study
H Zhu, L Shi, R Wang, L Cui, J Wang, M Tang… - Frontiers in …, 2022 - frontiersin.org
Objectives The aim of this study was to evaluate the global scientific output of research on
infertility and psychology; explore the current status and trends in this field through the …
infertility and psychology; explore the current status and trends in this field through the …
Decreased oocyte quality in patients with endometriosis is closely related to abnormal granulosa cells
W Fan, Z Yuan, M Li, Y Zhang, F Nan - Frontiers in Endocrinology, 2023 - frontiersin.org
Infertility and menstrual abnormalities in endometriosis patients are frequently caused by
aberrant follicular growth or a reduced ovarian reserve. Endometriosis typically does not …
aberrant follicular growth or a reduced ovarian reserve. Endometriosis typically does not …
Advanced Maternal Age‐associated SIRT1 Deficiency Compromises Trophoblast Epithelial− Mesenchymal Transition through an Increase in Vimentin Acetylation
L Xiong, X Ye, Z Chen, H Fu, S Li, P Xu, J Yu… - Aging cell, 2021 - Wiley Online Library
Advanced maternal age (AMA) pregnancies are rapidly increasing and are associated with
aberrant trophoblast cell function, poor placentation, and unfavorable pregnancy outcomes …
aberrant trophoblast cell function, poor placentation, and unfavorable pregnancy outcomes …
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