[引用][C] Female reproductive aging and oxidative stress: mesenchymal stem cell conditioned medium as a promising antioxidant

K Ra, SC Park, BC Lee - International Journal of Molecular Sciences, 2023 - MDPI

Sirt3 deficiency accelerates ovarian senescence without affecting spermatogenesis in aging mice

J Zhu, Q Yang, H Li, Y Wang, Y Jiang, H Wang… - Free Radical Biology …, 2022 - Elsevier
Abstract Sirtuin-3 (SIRT3), the main deacetylase in the mitochondria, maintains cellular
energy metabolism and redox balance by deacetylating mitochondrial proteins in a NAD+ …

Stem cell-based therapeutic strategies for premature ovarian insufficiency and infertility: a focus on aging

I Ali, AA Padhiar, T Wang, L He, M Chen, S Wu, Y Zhou… - Cells, 2022 - mdpi.com
Reproductive aging is on the rise globally and inseparable from the entire aging process. An
extreme form of reproductive aging is premature ovarian insufficiency (POI), which to date …

RAB7 activity is required for the regulation of mitophagy in oocyte meiosis and oocyte quality control during ovarian aging

X Jin, K Wang, L Wang, W Liu, C Zhang, Y Qiu, W Liu… - Autophagy, 2022 - Taylor & Francis
There is increasing evidence that mitophagy, a specialized form of autophagy to degrade
and clear long-lived or damaged mitochondria, is impaired in aging and age-related …

Control of mitochondrial integrity influences oocyte quality during reproductive aging

SA Khan, L Reed, WB Schoolcraft… - Molecular Human …, 2023 - academic.oup.com
Reduced quality in oocytes from women of advanced maternal age (AMA) is associated with
dysfunctional mitochondria. The objective of this study was to investigate the mechanisms …

[HTML][HTML] Daphnia as a model organism to probe biological responses to nanomaterials—from individual to population effects via adverse outcome pathways

K Reilly, LJA Ellis, HH Davoudi, S Supian… - Frontiers in …, 2023 - frontiersin.org
The importance of the cladoceran Daphnia as a model organism for ecotoxicity testing has
been well-established since the 1980s when it was standardised for regulatory testing of …

Does coenzyme Q10 supplementation improve fertility outcomes in women undergoing assisted reproductive technology procedures? A systematic review and meta …

P Florou, P Anagnostis, P Theocharis… - Journal of assisted …, 2020 - Springer
Objective Increased oxidative stress has been identified as a pathogenetic mechanism in
female infertility. However, the effect of specific antioxidants, such as coenzyme Q 10 (CoQ …

[HTML][HTML] Global research trends on infertility and psychology from the past two decades: a bibliometric and visualized study

H Zhu, L Shi, R Wang, L Cui, J Wang, M Tang… - Frontiers in …, 2022 - frontiersin.org
Objectives The aim of this study was to evaluate the global scientific output of research on
infertility and psychology; explore the current status and trends in this field through the …

Decreased oocyte quality in patients with endometriosis is closely related to abnormal granulosa cells

W Fan, Z Yuan, M Li, Y Zhang, F Nan - Frontiers in Endocrinology, 2023 - frontiersin.org
Infertility and menstrual abnormalities in endometriosis patients are frequently caused by
aberrant follicular growth or a reduced ovarian reserve. Endometriosis typically does not …

Advanced Maternal Age‐associated SIRT1 Deficiency Compromises Trophoblast Epithelial− Mesenchymal Transition through an Increase in Vimentin Acetylation

L Xiong, X Ye, Z Chen, H Fu, S Li, P Xu, J Yu… - Aging cell, 2021 - Wiley Online Library
Advanced maternal age (AMA) pregnancies are rapidly increasing and are associated with
aberrant trophoblast cell function, poor placentation, and unfavorable pregnancy outcomes …
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