Timing of thyroid hormone action in the developing brain: clinical observations and experimental findings

RT Zoeller, J Rovet - Journal of neuroendocrinology, 2004 - Wiley Online Library
The original concept of the critical period of thyroid hormone (TH) action on brain
development was proposed to identify the postnatal period during which TH supplement …

The thyroid‐brain interaction in thyroid disorders and mood disorders

M Bauer, T Goetz, T Glenn… - Journal of …, 2008 - Wiley Online Library
Thyroid hormones play a critical role in the metabolic activity of the adult brain, and
neuropsychiatric manifestations of thyroid disease have long been recognised. However, it …

Trophic action of leptin on hypothalamic neurons that regulate feeding

SG Bouret, SJ Draper, RB Simerly - Science, 2004 - science.org
In adult mammals, the adipocyte-derived hormone leptin acts on the brain to reduce food
intake by regulating the activity of neurons in the arcuate nucleus of the hypothalamus …

Rapid rewiring of arcuate nucleus feeding circuits by leptin

S Pinto, AG Roseberry, H Liu, S Diano… - science, 2004 - science.org
The fat-derived hormone leptin regulates energy balance in part by modulating the activity of
neuropeptide Y and proopiomelanocortin neurons in the hypothalamic arcuate nucleus. To …

[HTML][HTML] A novel syndrome combining thyroid and neurological abnormalities is associated with mutations in a monocarboxylate transporter gene

AM Dumitrescu, XH Liao, TB Best, K Brockmann… - The American Journal of …, 2004 - cell.com
Thyroid hormones are iodothyronines that control growth and development, as well as brain
function and metabolism. Although thyroid hormone deficiency can be caused by defects of …

Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation

ECH Friesema, A Grueters, H Biebermann, H Krude… - The Lancet, 2004 - thelancet.com
Summary Monocarboxylate transporter 8 (MCT8) is a thyroid hormone transporter, the gene
of which is located on the X chromosome. We tested whether mutations in MCT8 cause …

[HTML][HTML] Hypothalamic tanycytes: potential roles in the control of feeding and energy balance

M Bolborea, N Dale - Trends in neurosciences, 2013 - cell.com
Tanycytes, glial-like cells that line the third ventricle, are emerging as components of the
hypothalamic networks that control body weight and energy balance. They contact the …

APL regulates vascular tissue identity in Arabidopsis

M Bonke, S Thitamadee, AP Mähönen, MT Hauser… - Nature, 2003 - nature.com
Vascular plants have a long-distance transport system consisting of two tissue types with
elongated cell files, phloem and xylem. Phloem has two basic cell types, enucleate sieve …

General background on the hypothalamic-pituitary-thyroid (HPT) axis

RT Zoeller, SW Tan, RW Tyl - Critical reviews in toxicology, 2007 - Taylor & Francis
This article reviews the thyroid system, mainly from a mammalian standpoint. However, the
thyroid system is highly conserved among vertebrate species, so the general information on …

Light-induced hormone conversion of T4 to T3 regulates photoperiodic response of gonads in birds

T Yoshimura, S Yasuo, M Watanabe, M Iigo… - Nature, 2003 - nature.com
Reproduction of many temperate zone birds is under photoperiodic control. The Japanese
quail is an excellent model for studying the mechanism of photoperiodic time measurement …