RNA and single-stranded DNA (ssDNA) phages make up an understudied subset of
bacteriophages that have been rapidly expanding in the last decade thanks to …

Many bacterial surface glycans such as the peptidoglycan (PG) cell wall are built from
monomeric units linked to a polyprenyl lipid carrier. How this limiting carrier is distributed …

Bacteriophages (phages) are viruses specific to bacteria that target them with great
efficiency and specificity. Phages were first studied for their antibacterial potential in the …

Bacteriophages infect Gram-negative bacteria by attaching to molecules present on the
bacterial outer membrane, often lipopolysaccharides (LPS). Modification of the LPS can lead …

SlyD is a widely-occurring prokaryotic FKBP-family prolyl isomerase with an additional
chaperone domain. Often, such as in Escherichia coli, a third domain is found at its C …

Viral strategies to lyse host microbes can sometimes involve just a single gene, although the
mechanism of action can be hard to discern. In Science, Orta et al. present structures of a …

Phages and bacteria have a long history of co-evolution. However, these dynamics of phage-
host interactions are still largely unknown; identification of phage inhibitors that remodel host …

The ability of bacteria and viruses to selectively replicate in tumors has led to synthetic
engineering of new microbial therapies. Here we design a cooperative strategy whereby S …

Bacterial ghosts (BGs) are hollow bacterial cell envelopes with intact cellular structures,
presenting as promising candidates for various biotechnological and biomedical …

With the emergence of widespread antibiotic resistance, phages are an appealing
alternative to antibiotics in the fight against multidrug-resistant bacteria. Over the past few …