Adipocytes control bone mass, but the mechanism is unclear. To explore the effect of
postnatal adipocyte elimination on bone cells, we mated mice expressing an inducible …

Osteoporosis is a chronic condition characterized by decreased bone mass, loss of skeletal
integrity, and increased susceptibility to fracture. Drugs used to treat osteoporosis can be …

Non-invasive and/or non-destructive techniques can provide structural information about
bone, beyond simple bone densitometry. While the latter provides important information …

The selective cathepsin K inhibitor odanacatib (ODN) progressively increased bone mineral
density (BMD) and decreased bone‐resorption markers during 2 years of treatment in …

The most widely used medications for the treatment of osteoporosis are currently
bisphosphonates (BPs) and denosumab (Dmab). Both are antiresorptives, thus targeting the …

Introduction The Global Burden of Disease Study 2010 estimated the worldwide health
burden of 291 diseases and injuries and 67 risk factors by calculating disability-adjusted life …

Introduction The aim was to analyse data on the use of biochemical bone turnover markers
(BTM) in postmenopausal osteoporosis. Methods We carried out a comparative analysis of …

This review focuses on new developments and current controversies in the field of
quantitative computed tomography. Recent positions of the International Society for Clinical …

Osteoporosis is described as a silent disease prior to fracture, and the sequelae of an
osteoporotic fracture can be devastating. Primary care providers should routinely assess …

Now in its Tenth Edition and in continuous publication since 1959, Apley & Solomon's
System of Orthopaedics and Trauma is one of the world's leading textbooks of orthopaedic …