Osteoporotic fractures result in significant morbidity and mortality. Anabolic agents reverse
the negative skeletal balance that characterizes osteoporosis by stimulating osteoblast …

The impact of parathyroidectomy (PTX) on the long-term risks for hip and other fractures is
unknown. Uncontrolled case series have reported an increase in bone mineral density after …

Osteoporosis affects approximately 8 million women and 2 million men in the United States.
The associated fractures are a common and preventable cause of morbidity and mortality in …

Osteoporosis is characterized by the occurrence of fragility fractures. Over the past years,
various treatment options have become available, mostly antiresorptive agents such as …

Skeletal anabolic agents enhance bone formation, which is determined by the number and
function of osteoblasts. Signals that influence the differentiation and function of cells of the …

Abstract Purpose of Review The purpose is to review the efficacy and optimal use of
parathyroid hormone and parathyroid hormone-related protein analogs in osteoporosis …

Bisphosphonates are effective in reducing bone turnover, increasing BMD and reducing
fracture risk in postmenopausal women with osteoporosis. The licensed bisphosphonates …

Osteoporosis is a disorder with major impact in Western society and globally, and
osteoporotic fractures are associated with significant burden of health care cost, morbidity …

The separate and combined effects of intermittent parathyroid hormone (iPTH)(1–34) and
mechanical loading were assessed at trabecular and cortical sites of mouse long bones …

The number of patients on long-term anti-osteoporotic drug therapy is rising. Unfortunately,
there are few data to guide decisions about duration of pharmacologic therapy for …