MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …

Kaposi's sarcoma associated herpesvirus (KSHV), like other human herpes viruses,
establishes a biphasic life cycle referred to as dormant or latent, and productive or lytic …

Abstract N6-methyladenosine (m6A) and N6, 2′-O-dimethyladenosine (m6Am)
modifications (m6A/m) of messenger RNA mediate diverse cellular functions. Oncogenic …

The parameters involved in human cytomegalovirus (HCMV) latent infection in CD14 (+) and
CD34 (+) cells remain poorly identified. Using next generation sequencing we deduced the …

Epstein–Barr virus (EBV) was first discovered in 1964, and was the first known human tumor
virus now shown to be associated with a vast number of human diseases. Numerous studies …

Kaposi's sarcoma-associated herpesvirus (KSHV) is a double-stranded DNA virus with the
capacity to establish life-long latent infection. During latent infection, the viral genome …

Sirtuins are a family of nicotinamide adenine dinucleotide (NAD)+-dependent histone
deacetylases, comprising seven members SIRT1-SIRT7. Sirtuins have been extensively …

Kaposi's sarcoma-associated herpesvirus (KSHV) primarily persists as a latent episome in
infected cells. During latent infection, only a limited number of viral genes are expressed that …

Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus-8
(HHV-8), is etiologically linked to the development of Kaposi's sarcoma, primary effusion …

Latency establishment is the hallmark feature of herpesviruses, a group of viruses, of which
nine are known to infect humans. They have co-evolved alongside their hosts, and mastered …