[HTML][HTML] Mechanisms that regulate the activities of TET proteins
K Joshi, S Liu, P Breslin SJ, J Zhang - Cellular and Molecular Life Sciences, 2022 - Springer
The ten–eleven translocation (TET) family of dioxygenases consists of three members,
TET1, TET2, and TET3. All three TET enzymes have Fe+ 2 and α-ketoglutarate (α-KG) …
TET1, TET2, and TET3. All three TET enzymes have Fe+ 2 and α-ketoglutarate (α-KG) …
[HTML][HTML] DNA methylation malleability and dysregulation in cancer progression: Understanding the role of PARP1
R Srivastava, N Lodhi - Biomolecules, 2022 - mdpi.com
Mammalian genomic DNA methylation represents a key epigenetic modification and its
dynamic regulation that fine-tunes the gene expression of multiple pathways during …
dynamic regulation that fine-tunes the gene expression of multiple pathways during …
Detection of human urinary 5-hydroxymethylcytosine by stable isotope dilution HPLC-MS/MS analysis
The sixth DNA base 5-hydroxymethylcytosine (5hmC) is the major oxidation product of the
epigenetic modification 5-methylcytosine (5mC), mediating DNA demethylation in mammals …
epigenetic modification 5-methylcytosine (5mC), mediating DNA demethylation in mammals …
[HTML][HTML] OCT4 maintains self-renewal and reverses senescence in human hair follicle mesenchymal stem cells through the downregulation of p21 by DNA …
Y Lu, H Qu, D Qi, W Xu, S Liu, X Jin, P Song… - Stem cell research & …, 2019 - Springer
Background Self-renewal is dependent on an intrinsic gene regulatory network centered on
OCT4 and on an atypical cell cycle G1/S transition, which is also regulated by OCT4. p21, a …
OCT4 and on an atypical cell cycle G1/S transition, which is also regulated by OCT4. p21, a …
5-Hydroxymethylcytosine glucosylation-triggered helicase-dependent amplification-based fluorescent biosensor for sensitive detection of β-glucosyltransferase with …
β-glucosyltransferase (β-GT) catalyzes the glucosylation of 5-hydroxymethylcytosine (5-
hmC) to enable the survival of bacteriophage and parasite in host cells, and it is a critical …
hmC) to enable the survival of bacteriophage and parasite in host cells, and it is a critical …
Pan-precancer and cancer DNA methylation profiles revealed significant tissue specificity of interrupted biological processes in tumorigenesis
ABSTRACT DNA methylation (DNAme) alterations are known to initiate from the
precancerous stage of tumorigenesis. Herein, we investigated the global and local patterns …
precancerous stage of tumorigenesis. Herein, we investigated the global and local patterns …
大气PM2.5暴露对DNA甲基化的影响
余秀蓉， 孟喆， 李明月， 谢淑娟， 洪新如， 刘超斌 - 环境与职业医学, 2020 - jeom.org
当今, 中国乃至全球普遍存在空气污染问题. 作为空气污染物主要成分的细颗粒物(PM 2.5),
其对健康的影响已引起国内外的高度关注. PM 2.5 的毒性成分主要是重金属和多环芳烃等 …
其对健康的影响已引起国内外的高度关注. PM 2.5 的毒性成分主要是重金属和多环芳烃等 …
Fotoduyarlı biyomalzemelerle uygulanan fotodinamik terapi'nin epigenetik mekanizmalara etkisi
M Yıldız - 2022 - dspace.trakya.edu.tr
Özet Fotodinamik terapi ile indüklenen, akut oksidatif strese maruz kalan hücrelerin, bu
strese vereceği yanıtta genetik ve epigenetik değişikliklerin olası bağlantısına odaklandık …
strese vereceği yanıtta genetik ve epigenetik değişikliklerin olası bağlantısına odaklandık …
A Label-Free Electrochemical Biosensor for Sensitive Detection of 5-Hydroxymethylcytosine
L Cui, J Hu, M Wang, CC Li, CY Zhang - DNA Modification Detection …, 2022 - Springer
Abstract The 5-hydroxymethylcytosine (5-hmC) is regarded as sixth base in the genome and
closely linked to a series of physiological and pathological processes. Nevertheless, the …
closely linked to a series of physiological and pathological processes. Nevertheless, the …
Effects of atmospheric PM2.5 exposure on DNA methylation
YU Xiu-rong, M Zhe, LI Ming-yue, XIE Shu-juan… - … of Environmental and …, 2020 - jeom.org
Air pollution is common in China and throughout the world. Fine particulate matter (PM 2.5)
is a main air pollutant carrying toxic components, and its impacts on human health have …
is a main air pollutant carrying toxic components, and its impacts on human health have …