The principal role of prolactin in mammals is the regulation of lactation. Prolactin is a
hormone that is mainly synthesized and secreted by lactotroph cells in the anterior pituitary …

In this narrative review, the biological/biochemical impact (toxicity) of a large array of known
individual uremic retention solutes and groups of solutes is summarized. We classified these …

Chronic kidney disease affects 10% of the population with notable differences in ethnic and
sex-related susceptibility to kidney injury and disease. Kidney dysfunction leads to …

Beside cytotoxic drugs, other drugs can impact men's fertility through various mechanisms.
Via the modification of the hypothalamic–pituitary–gonadal axis hormones or by non …

Organisms experience dramatic fluctuations in demands and stresses over the course of the
day. In order to maintain biological processes within physiological boundaries, mechanisms …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) affecting young people and leading to demyelination and neurodegeneration. The …

The hypothalamic control of prolactin secretion is different from other anterior pituitary
hormones, in that it is predominantly inhibitory, by means of dopamine from the …

Since the 1970s, clinicians have increasingly become more familiar with hyperprolactinemia
(HPRL) as a common adverse effect of antipsychotic medication, which remains the …

The reverse transcription polymerase chain reaction (RT-PCR) is the most sensitive method
for the detection of low-abundance mRNA, often obtained from limited tissue samples …

The mammary gland is a compound, branched tubuloalveolar structure and a major
characteristic of mammals. The mammary gland has evolved from epidermal apocrine …