High-throughput screening: today's biochemical and cell-based approaches

V Blay, B Tolani, SP Ho, MR Arkin - Drug Discovery Today, 2020 - Elsevier
Highlights•Self-contained overview of current high-throughput screening technologies.•
Expands on the current use of most recent tools, like high-throughput microscopy.•Learn …

A Review of the Role of Green Tea (Camellia sinensis) in Antiphotoaging, Stress Resistance, Neuroprotection, and Autophagy

MI Prasanth, BS Sivamaruthi, C Chaiyasut… - Nutrients, 2019 - mdpi.com
Tea is one of the most widely consumed beverages worldwide, and is available in various
forms. Green tea is richer in antioxidants compared to other forms of tea. Tea is composed of …

[HTML][HTML] Alternatives to animal testing: A review

SK Doke, SC Dhawale - Saudi Pharmaceutical Journal, 2015 - Elsevier
The number of animals used in research has increased with the advancement of research
and development in medical technology. Every year, millions of experimental animals are …

Chitosan overlaid Fe3O4/rGO nanocomposite for targeted drug delivery, imaging, and biomedical applications

V Karthika, MS AlSalhi, S Devanesan, K Gopinath… - Scientific Reports, 2020 - nature.com
A hybrid and straightforward nanosystem that can be used simultaneously for cancer-
targeted fluorescence imaging and targeted drug delivery in vitro was reported in this study …

[HTML][HTML] Artificial intelligence in pharmaceutical sciences

M Lu, J Yin, Q Zhu, G Lin, M Mou, F Liu, Z Pan, N You… - Engineering, 2023 - Elsevier
Drug discovery and development affects various aspects of human health and dramatically
impacts the pharmaceutical market. However, investments in a new drug often go …

Phenotypic screens as a renewed approach for drug discovery

W Zheng, N Thorne, JC McKew - Drug discovery today, 2013 - Elsevier
Highlights•Phenotypic screening is a renewed approach for lead discovery.•Phenotypic
screen approach may improve the success rate of drug approval.•New drug targets can be …

Droplet microarrays: from surface patterning to high‐throughput applications

W Feng, E Ueda, PA Levkin - Advanced materials, 2018 - Wiley Online Library
High‐throughput screening of live cells and chemical reactions in isolated droplets is an
important and growing method in areas ranging from studies of gene functions and the …

[HTML][HTML] Drosophila–a versatile model in biology & medicine

BH Jennings - Materials today, 2011 - Elsevier
The fruit fly Drosophila melanogaster is a versatile model organism that has been used in
biomedical research for over a century to study a broad range of phenomena. There are …

The utility of zebrafish as a model for screening developmental neurotoxicity

M d'Amora, S Giordani - Frontiers in neuroscience, 2018 - frontiersin.org
The developing central nervous system and the blood brain barrier are especially
vulnerable and sensitive to different chemicals, including environmental contaminants and …

Animal models of pain: diversity and benefits

C Abboud, A Duveau, R Bouali-Benazzouz… - Journal of neuroscience …, 2021 - Elsevier
Chronic pain is a maladaptive neurological disease that remains a major health problem. A
deepening of our knowledge on mechanisms that cause pain is a prerequisite to developing …