[HTML][HTML] The ketogenic diet and cardiovascular diseases

D Dyńka, K Kowalcze, A Charuta, A Paziewska - Nutrients, 2023 - mdpi.com
The most common and increasing causes of death worldwide are cardiovascular diseases
(CVD). Taking into account the fact that diet is a key factor, it is worth exploring this aspect of …

Dietary approaches for exploiting metabolic vulnerabilities in cancer

O Menyhárt, B Győrffy - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
Renewed interest in tumor metabolism sparked an enthusiasm for dietary interventions to
prevent and treat cancer. Changes in diet impact circulating nutrient levels in the plasma …

[HTML][HTML] Molecular Mechanisms of Neuroprotection by Ketone Bodies and Ketogenic Diet in Cerebral Ischemia and Neurodegenerative Diseases

J Jang, SR Kim, JE Lee, S Lee, HJ Son… - International journal of …, 2023 - mdpi.com
Ketone bodies (KBs), such as acetoacetate and β-hydroxybutyrate, serve as crucial
alternative energy sources during glucose deficiency. KBs, generated through ketogenesis …

[HTML][HTML] β-HB treatment reverses sorafenib resistance by shifting glycolysis–lactate metabolism in HCC

FM Suk, CY Wu, CC Fang, TL Chen, YJ Liao - Biomedicine & …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is the most common primary malignant tumor. Although
sorafenib and regorafenib have been approved for first-line and second-line treatment …

[HTML][HTML] Ketone Bodies in Diabetes Mellitus: Friend or Foe?

S Veneti, MG Grammatikopoulou, E Kintiraki… - Nutrients, 2023 - mdpi.com
In glucose-deprived conditions, ketone bodies are produced by the liver mitochondria,
through the catabolism of fatty acids, and are used peripherally, as an alternative energy …

[HTML][HTML] The physiological and pathological role of acyl-coA oxidation

S Szrok-Jurga, A Czumaj, J Turyn… - International Journal of …, 2023 - mdpi.com
Fatty acid metabolism, including β-oxidation (βOX), plays an important role in human
physiology and pathology. βOX is an essential process in the energy metabolism of most …

[HTML][HTML] New Insights into the Identification of Metabolites and Cytokines Predictive of Outcome for Patients with Severe SARS-CoV-2 Infection Showed Similarity with …

S Costantini, G Madonna, E Di Gennaro… - International Journal of …, 2023 - mdpi.com
SARS-CoV-2 infection is characterized by several clinical manifestations, ranging from the
absence of symptoms to severe forms that necessitate intensive care treatment. It is known …

Improved therapy for clear cell renal cell carcinoma: beta-hydroxybutyrate and quercetin target hypoxia-induced angiogenesis and multidrug resistance

N Mohammadipoor, R Naiebi, SA Mazhari… - Molecular Biology …, 2024 - Springer
Background Clear cell renal cell carcinoma (ccRCC) is a form of kidney cancer
characterized by dysregulated angiogenesis and multidrug resistance. Hypoxia-induced …

Is there a role for ketones as alternative fuel in critical illness?

N Watson, TJ McClelland… - Current Opinion in …, 2023 - journals.lww.com
Is there a role for ketones as alternative fuel in critical... : Current Opinion in Critical Care Is there
a role for ketones as alternative fuel in critical illness? : Current Opinion in Critical Care Log in or …

Targeting apoptosis and unfolded protein response: the impact of β-hydroxybutyrate in clear cell renal cell carcinoma under glucose-deprived conditions

F Roohy, M Siri, K Kohansal, A Ghalandari… - Molecular Biology …, 2024 - Springer
Background Clear cell renal cell carcinoma (ccRCC) plays a significant role in the mortality
associated with kidney cancer. Targeting biological processes that inhibit cancer growth …