Being a bioactive material, hydroxyapatite (HAp) is regarded as one of the most attractive
ceramic biomaterials for bone and hard-tissue replacement and regeneration. Despite its …

Acting as a bridge between the cytoskeleton of the cell and the extra cellular matrix (ECM),
the cell-ECM adhesions with integrins at their core, play a major role in cell signalling to …

Although artificial bone repair scaffolds, such as titanium alloy, bioactive glass, and
hydroxyapatite (HAp), have been widely used for treatment of large‐size bone defects or …

The regeneration of hierarchical osteochondral units is challenging due to difficulties in
inducing spatial, directional and controllable differentiation of mesenchymal stem cells …

One of the major issues in tissue engineering is regulation of stem cell differentiation toward
specific lineages. Unlike biological and chemical signals, physical signals with adjustable …

Physical cues like morphology, light, electric signal, mechanic signal, magnetic signal, and
heat can be used as alternative regulators for expensive but short‐acting growth factors in …

There is an evident advantage in personalized customization of orthopedic implants by 3D-
printed titanium (Ti) and its alloys. However, 3D-printed Ti alloys have a rough surface …

Biochemical signals, such as growth factors, cytokines, and transcription factors are known
to play a crucial role in regulating a variety of cellular activities as well as maintaining the …

Large bone defects are a major global health concern. Bone tissue engineering (BTE) is the
most promising alternative to avoid the drawbacks of autograft and allograft bone …

Abstrct Polycaprolactone/hydroxyapatite (PCL/HA) composite coating was fabricated by a
combination of hydrothermal and dipping methods to delay the degradation of Mg alloy …