Toxoplasma gondii is a protozoan parasite that is the causative agent of toxoplasmosis, an
infection with high prevalence worldwide. Most of the infected individuals are either …

Early electron microscopy studies revealed the elaborate cellular features that define the
unique adaptations of apicomplexan parasites. Among these were bulbous rhoptry (ROP) …

Over the past two decades, molecular and cell biologists have made important progress in
characterizing the components and compartments of the cell. New visualization methods …

The eukaryotic phylum Apicomplexa encompasses thousands of obligate intracellular
parasites of humans and animals with immense socio-economic and health impacts. We …

▪ Abstract Golgi inheritance proceeds via sequential biogenesis and partitioning phases.
Although little is known about Golgi growth and replication (biogenesis), ultrastructural and …

The protozoan phylum Apicomplexa encompasses∼ 5000 species of obligate intracellular
parasites, including those responsible for malaria and toxoplasmosis. Rather than dividing …

Since its first visualization in 1898, the Golgi has been a topic of intense morphological
research. A typical mammalian Golgi consists of a pile of stapled cisternae, the Golgi stack …

Together with micronemes and rhoptries, dense granules are specialised secretory
organelles of Apicomplexa parasites. Among Apicomplexa, Plasmodium represents a model …

Rab GTPases control vesicle movement and tethering membrane events in membrane
trafficking. We used the 38 human Rab GTPase activating proteins (GAPs) to identify which …

In the apicomplexans, endocytosed cargos (eg, hemoglobin) are trafficked to a specialized
organelle for digestion. This follows a unique endocytotic process at the …