Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management

JS Knight, DW Branch, TL Ortel - bmj, 2023 - bmj.com
Antiphospholipid syndrome (APS) is a thrombo-inflammatory disease propelled by
circulating autoantibodies that recognize cell surface phospholipids and phospholipid …

The 2023 ACR/EULAR antiphospholipid syndrome classification criteria

M Barbhaiya, S Zuily, R Naden, A Hendry… - Arthritis & …, 2023 - Wiley Online Library
Objective To develop new antiphospholipid syndrome (APS) classification criteria with high
specificity for use in observational studies and trials, jointly supported by the American …

Antiphospholipid syndrome management: a 2023 update and practical algorithm-based approach

A Ambati, JS Knight, Y Zuo - Current Opinion in Rheumatology, 2023 - journals.lww.com
Although the knowledge of APS pathogenesis has grown in recent years, the management
principles and strategies are largely unchanged. There is an unmet need for evaluating …

Neutrophil glucose flux as a therapeutic target in antiphospholipid syndrome

A Tambralli, A Harbaugh… - The Journal of …, 2024 - Am Soc Clin Investig
Neutrophil hyperactivity and neutrophil extracellular trap release (NETosis) appear to play
important roles in the pathogenesis of the thromboinflammatory autoimmune disease known …

[HTML][HTML] Thrombosis and antiphospholipid antibodies in Japanese COVID-19: based on propensity score matching

S Oba, T Hosoya, R Kaneshige, D Kawata… - Frontiers in …, 2023 - frontiersin.org
Background Thrombosis is a unique complication of coronavirus disease 2019 (COVID-19).
Although antiphospholipid antibodies (aPL) are detected in COVID-19 patients, their clinical …

Assessing disease activity and damage in antiphospholipid syndrome

D Andrade, MG Tektonidou - Clinical Immunology, 2023 - Elsevier
Antiphospholipid syndrome (APS) has been characterized by a variety of vascular and
pregnancy manifestations related to an interplay between thrombotic and inflammatory …

Associations among antiphospholipid antibody types, isotypes, and titers: an antiphospholipid syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS …

E Gkrouzman, R Willis, D Andrade, MG Tektonidou… - Laboratory …, 2023 - Elsevier
Several antiphospholipid antibody (aPL) profiles (“triple” and lupus anticoagulant [LA]
positivity) are associated with a higher risk for clinical manifestations of antiphospholipid …

Epidemiology of antiphospholipid syndrome: macro-and microvascular manifestations

P Gaspar, S Sciascia, MG Tektonidou - Rheumatology, 2024 - academic.oup.com
Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by
thrombotic and non-thrombotic macro-and microvascular manifestations and pregnancy …

Damage measured by Damage Index for Antiphospholipid Syndrome (DIAPS) in antiphospholipid antibody-positive patients included in the APS ACTION registry

GGM Balbi, Y Ahmadzadeh, MG Tektonidou… - …, 2024 - academic.oup.com
Objectives Our primary objective was to quantify damage burden measured by Damage
Index for Antiphospholipid Syndrome (DIAPS) in aPL-positive patients with or without a …

[HTML][HTML] Prevalence and adverse consequences of delayed diagnosis and misdiagnosis in thrombotic antiphospholipid syndrome. An observational cohort study and …

A Ruffatti, M Tonello, A Calligaro, T Del Ross… - Clinical …, 2023 - Springer
Obiectives This study aims to prospectively evaluate the frequency and adverse
consequences of diagnostic delay and misdiagnosis in a cohort of patients with thrombotic …