As the basic unit of life, cells are compartmentalized microreactors with molecularly crowded
microenvironments. The quest to understand the cell origin inspires the design of synthetic …

Liquid–liquid phase separation (LLPS) of biomolecules inspires the construction of
protocells and drives the formation of cellular membraneless organelles. The resulting …

The design of compartmentalized colloids that exhibit biomimetic properties is providing
model systems for developing synthetic cell-like entities (protocells). Inspired by the cell …

Abstract Design of reversible organelle‐like microcompartments formed by liquid–liquid
phase separation in cell‐mimicking entities has significantly advanced the bottom‐up …

As the preliminary synthetic analogs of living cells, protocells with life‐like features serve as
a versatile platform to explore the origin of life. Although protocells constructed from multiple …

Many biopolymers are highly charged, and as in the case of many polymer mixtures, they
tend to phase separate as a natural consequence of chain connectivity and an associated …

The investigation of the interplay between complex coacervate microdroplets and
amphiphilic molecules offers valuable insights into the processes of prebiotic …

Liquid-liquid phase separation (LLPS) or biomolecular condensation that leads to formation
of membraneless organelles plays a critical role in many biochemical processes …