The management of penile intraepithelial neoplasia (PeIN): clinical and histological features and treatment of 345 patients and a review of the literature

G Kravvas, L Ge, J Ng, TN Shim… - Journal of …, 2022 - Taylor & Francis
Abstract Introduction Penile intraepithelial neoplasia (PeIN) is a histological term for
precancerous penile lesions. PeIN is important due to the high morbidity and mortality …

Advances in the pathology of penile carcinomas

A Chaux, AL Cubilla - Human pathology, 2012 - Elsevier
The incidence of penile cancer varies from country to country, with the highest figures
reported for countries in Africa, South America, and Asia and lowest in the United States and …

Two major pathways of penile carcinogenesis: HPV-induced penile cancers overexpress p16ink4a, HPV-negative cancers associated with dermatoses express p53 …

S Mannweiler, S Sygulla, E Winter… - Journal of the American …, 2013 - Elsevier
BACKGROUND: Penile squamous cell carcinomas (SCC) arise either through transforming
infections with human papillomavirus (HPV) or independent of HPV, often in the background …

[HTML][HTML] Pathogenesis of penile squamous cell carcinoma: molecular update and systematic review

I Ribera-Cortada, J Guerrero-Pineda, I Trias… - International Journal of …, 2021 - mdpi.com
Penile squamous cell carcinoma (PSCC) is a rare but aggressive neoplasm with dual
pathogenesis (human papillomavirus (HPV)-associated and HPV-independent). The …

Pathophysiological basis of human papillomavirus in penile cancer: Key to prevention and delivery of more effective therapies

PE Spiess, J Dhillon, AS Baumgarten… - CA: A Cancer …, 2016 - Wiley Online Library
Answer questions and earn CME/CNE Squamous cell carcinoma (SCC) of the penis is a
rare malignancy in the United States, with a significantly higher incidence—up to 20 to 30 …

WHO 2022 classification of penile and scrotal cancers: updates and evolution

S Menon, H Moch, DM Berney, IA Cree… - …, 2023 - Wiley Online Library
Squamous cell carcinoma (SCC) is the most common malignant tumour of the penis. The
2022 WHO classification reinforces the 2016 classification and subclassifies precursor …

Expression of p53, p21 and cyclin D1 in penile cancer: p53 predicts poor prognosis

S Gunia, C Kakies, A Erbersdobler… - Journal of clinical …, 2012 - jcp.bmj.com
Aims To evaluate the role of p53, p21 and cyclin D1 expression in patients with penile
cancer (PC). Methods Paraffin-embedded tissues from PC specimens from six pathology …

Distribution and characterization of subtypes of penile intraepithelial neoplasia and their association with invasive carcinomas: a pathological study of 139 lesions in …

A Chaux, EF Velazquez, A Amin, A Soskin, R Pfannl… - Human pathology, 2012 - Elsevier
We are presenting the morphological features of 121 cases of atypical penile intraepithelial
lesions. The term penile intraepithelial neoplasia (PeIN) was used to encompass all of them …

Verruciform and condyloma-like squamous proliferations in the anogenital region

MP Chan - Archives of Pathology & Laboratory Medicine, 2019 - meridian.allenpress.com
Context.—Histologic distinction between condyloma acuminatum and various benign and
malignant condyloma-like lesions in the anogenital area poses a common diagnostic …

Histologic classification of penile intraepithelial neoplasia

EF Velazquez, A Chaux, AL Cubilla - Seminars in diagnostic pathology, 2012 - Elsevier
Penile squamous cell carcinomas (SCCs) and their corresponding precancerous lesions
can be classified in 2 major groups: human papillomavirus (HPV) related and HPV …