The intricate relationships between innate immunity and brain diseases raise increased
interest across the wide spectrum of neurodegenerative and neuropsychiatric disorders …

Functional MRI (fMRI) has been widely used to study abnormal patterns of brain connectivity
at rest and activation during a variety of tasks in patients with idiopathic Parkinson's disease …

The spreading hypothesis of neurodegeneration assumes an expansion of neural
pathologies along existing neural pathways. Multimodal neuroimaging studies have …

Longitudinal connectivity studies might guide our understanding of the underlying
neurodegenerative processes. We report the results of a longitudinal study in patients at …

Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD),
Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS) are heterogeneous …

Introduction The study aim was to identify longitudinal abnormalities of functional
connectivity and its relation with motor disability in early to moderately advanced stages of …

Purpose Parkinson's disease (PD) is primarily defined by motor symptoms and is associated
with alterations of sensorimotor areas. Evidence for network changes of the sensorimotor …

The synaptic organization of the brain is constantly modified by activity-dependent synaptic
plasticity. In several neurological disorders, abnormal neuronal activity and pathological …

To explore the effects of PD pathology on brain connectivity, we characterized with an
emergent computational approach the brain metabolic connectome using [18F] FDG-PET in …

This study aimed to identify functional neuroimaging patterns anticipating the clinical
indication for deep brain stimulation (DBS) in patients with Parkinson's disease (PD). A …