The Immune Response to Mycobacterium tuberculosis in HIV-1-Coinfected Persons
Globally, about 36.7 million people were living with HIV infection at the end of 2015. The
most frequent infection co-occurring with HIV-1 is Mycobacterium tuberculosis—374,000 …
most frequent infection co-occurring with HIV-1 is Mycobacterium tuberculosis—374,000 …
Tuberculosis IRIS: pathogenesis, presentation, and management across the spectrum of disease
CM Quinn, V Poplin, J Kasibante, K Yuquimpo… - Life, 2020 - mdpi.com
Antiretroviral therapy (ART), while essential in combatting tuberculosis (TB) and HIV
coinfection, is often complicated by the TB-associated immune reconstitution inflammatory …
coinfection, is often complicated by the TB-associated immune reconstitution inflammatory …
HIV infection and immune activation: the role of coinfections
A Boulougoura, I Sereti - Current Opinion in HIV and AIDS, 2016 - journals.lww.com
Better understanding of the role of opportunistic infections at ART initiation and IRIS
pathogenesis will assist in improved strategies for prevention and treatment. The long-term …
pathogenesis will assist in improved strategies for prevention and treatment. The long-term …
The tuberculosis-associated immune reconstitution inflammatory syndrome: recent advances in clinical and pathogenesis research
NF Walker, C Stek, S Wasserman… - Current Opinion in …, 2018 - journals.lww.com
Specific biomarkers would aid in identifying high-risk patients for interventions and a
diagnostic test is needed. Clinicians should consider prednisone for TB-IRIS prevention in …
diagnostic test is needed. Clinicians should consider prednisone for TB-IRIS prevention in …
Chronic immune activation in TB/HIV co-infection
HIV co-infection is the most critical risk factor for the reactivation of latent tuberculosis (TB)
infection (LTBI). While CD4+ T cell depletion has been considered the major cause of HIV …
infection (LTBI). While CD4+ T cell depletion has been considered the major cause of HIV …
[HTML][HTML] TB-IRIS pathogenesis and new strategies for intervention: Insights from related inflammatory disorders
In almost one in five HIV/tuberculosis (TB) co-infected patients, initiation of antiretroviral
therapy (ART) is complicated by TB immune reconstitution inflammatory syndrome (TB-IRIS) …
therapy (ART) is complicated by TB immune reconstitution inflammatory syndrome (TB-IRIS) …
Clinical and genetic markers associated with tuberculosis, HIV-1 infection, and TB/HIV-immune reconstitution inflammatory syndrome outcomes
NBR de Sá, M Ribeiro-Alves, TP da Silva… - BMC Infectious …, 2020 - Springer
Abstract Background Tuberculosis (TB) and AIDS are the leading causes of infectious
disease death worldwide. In some TB-HIV co-infected individuals treated for both diseases …
disease death worldwide. In some TB-HIV co-infected individuals treated for both diseases …
Differential expression of CXCR3 and CCR6 on CD4+ T-lymphocytes with distinct memory phenotypes characterizes tuberculosis-associated immune reconstitution …
PS Silveira-Mattos, G Narendran, K Akrami… - Scientific reports, 2019 - nature.com
Immune reconstitution inflammatory syndrome (IRIS) occurs in up to 40% of individuals co-
infected with pulmonary tuberculosis (PTB) and HIV, primarily upon antiretroviral therapy …
infected with pulmonary tuberculosis (PTB) and HIV, primarily upon antiretroviral therapy …
Robust Reconstitution of Tuberculosis-Specific Polyfunctional CD4+ T-Cell Responses and Rising Systemic Interleukin 6 in Paradoxical Tuberculosis-Associated …
S Ravimohan, N Tamuhla, K Nfanyana… - Clinical Infectious …, 2016 - academic.oup.com
Background. The immunopathogenesis of paradoxical tuberculosis-associated immune
reconstitution inflammatory syndrome (TB-IRIS) remains unclear. We determined the …
reconstitution inflammatory syndrome (TB-IRIS) remains unclear. We determined the …
Deregulated lncRNAs in B cells from patients with active tuberculosis
Y Fu, X Xu, J Xue, W Duan, Z Yi - PLoS One, 2017 - journals.plos.org
Role of lncRNAs in human adaptive immune response to TB infection is largely unexplored.
To address this issue, here we characterized lncRNA expression profile in primary human B …
To address this issue, here we characterized lncRNA expression profile in primary human B …