Publisher Summary This chapter discusses the interaction of human cytomegalovirus
(HCMV) with different host cells in vitro and in vivo. The role of different cell populations in …

Although there is no definitive evidence of the association of human cytomegalovirus
(HCMV) infection with human cancers, the oncogenic potential of HCMV has been well …

Human cytomegalovirus-infected fibroblasts are resistant to the induction of apoptosis by
superinfection with a mutant adenovirus unable to produce the viral E1B 19-kDa protein that …

Human cytomegalovirus (HCMV) is a widespread opportunistic pathogen that causes birth
defects in newborns and severe disease in immunocompromised individuals. The broad …

Human cytomegalovirus (HCMV) pathogenesis is characterized by multiple organ system
involvement due to viral spread to host organs after a cell-associated viremia. The cell type …

Infection of quiescent fibroblasts with human cytomegalovirus (HCMV) was found to cause a
rapid activation of cellular phosphatidylinositol 3-kinase (PI3-K). Maximum PI3-K activation …

During human cytomegalovirus (HCMV) infection, a series of regulated events take place
following virus binding and entry into the cell, including the upregulation of cellular …

Antiviral therapy of primary and recurrent infections with human cytomegalovirus is reserved
for severe manifestations and faces several limitations. Presently candidates for novel drugs …

The cellular transcription factors Sp1 and NF-kappaB were upregulated shortly after the
binding of purified live or UV-inactivated human cytomegalovirus (HCMV) to the cell surface …

To continue our investigation of the cellular events that occur following human CMV (HCMV)
infection, we focused on the regulation of cellular activation following viral binding to human …