Current trends and advancements in crystallization and single-crystal structural analysis of small molecules

Y Xiao, C Wu, L Zhou, P Commins, L Li… - Coordination Chemistry …, 2024 - Elsevier
The advancement of single-crystal structural analysis has emerged as a pivotal technology
surpassing spectroscopic methods in revealing the intricate structural details of organic …

Mechanochemical synthesis of cocrystal: From mechanism to application

Y Xiao, C Wu, X Hu, K Chen, L Qi, P Cui… - Crystal Growth & …, 2023 - ACS Publications
Cocrystal engineering is gaining interest across various disciplines since it can effectively
tune the properties of solid substances via noncovalent synthesis by introducing new …

Molecular insights into the formation of drug-polymer inclusion complex

B Liu, C Li, Z Chen, X Ou, S Li, A Li, P Chen… - International Journal of …, 2024 - Elsevier
Drug-polymer inclusion complex (IC) has been viewed as a novel solid form of drugs for
property modification. Nonetheless, our understanding of the formation mechanism remains …

Efficient Screening of Pharmaceutical Cocrystals by Microspacing In-Air Sublimation

H Li, L Wang, X Ye, C Yao, S Song, Y Qu… - Journal of the …, 2024 - ACS Publications
Cocrystal screening and single-crystal growth remain the primary obstacles in the
development of pharmaceutical cocrystals. Here, we present a new approach for cocrystal …

Two unique M-MOFs (M: Zn, Mn) based on various metal-oxygen chains for good sensitivity sensing and magnetic properties

YT Yan, W Cai, XD Fan, H Zhang, RR Hui… - Journal of Molecular …, 2023 - Elsevier
In this paper, two novel two-dimensional MOFs were synthesized by solvothermal reaction of
2, 4-di (2′, 5′-dicarboxylphenyl) benzoic acid ligand and Zn (Ⅱ) and Mn (Ⅱ) metal …

Understanding the formation mechanism of drug-polymer inclusion complex by structure elucidation and theoretical calculation

M Lu, B Liu, C Li, Z Chen, X Ou, S Li, A Li, P Chen - 2023 - chemrxiv.org
Drug-polymer inclusion complex (IC) has been considered a novel solid-state of drugs for
properties modification. However, the formation mechanism is poorly understood. This work …