[HTML][HTML] Possible Role of Cannabis in the Management of Neuroinflammation in Patients with Post-COVID Condition

N Cárdenas-Rodríguez, I Ignacio-Mejía… - International Journal of …, 2024 - mdpi.com
The post-COVID condition (PCC) is a pathology stemming from COVID-19, and studying its
pathophysiology, diagnosis, and treatment is crucial. Neuroinflammation causes the most …

[HTML][HTML] Pathology of pain and its implications for therapeutic interventions

B Cao, Q Xu, Y Shi, R Zhao, H Li, J Zheng… - … and Targeted Therapy, 2024 - nature.com
Pain is estimated to affect more than 20% of the global population, imposing incalculable
health and economic burdens. Effective pain management is crucial for individuals suffering …

[HTML][HTML] Cannabidiol treatment improves metabolic profile and decreases hypothalamic inflammation caused by maternal obesity

FS Rodrigues, J Jantsch, GF Fraga, VS Dias… - Frontiers in …, 2023 - frontiersin.org
Introduction The implications of maternal overnutrition on offspring metabolic and
neuroimmune development are well-known. Increasing evidence now suggests that …

[HTML][HTML] The selective CB2 agonist COR167 reduced symptoms in a mice model of trauma-induced peripheral neuropathy through HDAC-1 inhibition

V Borgonetti, C Mugnaini, F Corelli, N Galeotti - Biomedicines, 2023 - mdpi.com
Neuropathic pain is a chronic disabling condition with a 7–10% of prevalence in the general
population that is largely undertreated. Available analgesic therapies are poorly effective …

Cannabidiol prevents LPS-induced inflammation by inhibiting the NLRP3 inflammasome and iNOS activity in BV2 microglia cells via CB2 receptors and PPARγ

F da Silva Rodrigues, WR Newton, IDÁ Tassinari… - Neurochemistry …, 2024 - Elsevier
Neuroinflammation stands as a critical player in the pathogenesis of diverse neurological
disorders, with microglial cells playing a central role in orchestrating the inflammatory …

Novel Dual-Acting Hybrids Targeting Type-2 Cannabinoid Receptors and Cholinesterase Activity Show Neuroprotective Effects In Vitro and Amelioration of Cognitive …

C Mugnaini, A Brizzi, M Paolino… - ACS Chemical …, 2024 - ACS Publications
Alzheimer's disease (AD) is a neurodegenerative form of dementia characterized by the loss
of synapses and a progressive decline in cognitive abilities. Among current treatments for …

Cannabidiol ameliorates PTSD-like symptoms by inhibiting neuroinflammation through its action on CB2 receptors in the brain of male mice

G Xie, X Gao, Q Guo, H Liang, L Yao, W Li, B Ma… - Brain, Behavior, and …, 2024 - Elsevier
Post-traumatic stress disorder (PTSD) is a debilitating mental health disease related to
traumatic experience, and its treatment outcomes are unsatisfactory. Accumulating research …

[HTML][HTML] A new HPLC method with multiple detection systems for impurity analysis and discrimination of natural versus synthetic cannabidiol

V Brighenti, M Marani, C Caroli, L Bertarini… - Analytical and …, 2024 - Springer
Cannabidiol (CBD) is the main non-psychoactive phytocannabinoid derived from Cannabis
sativa L. It is now an active pharmaceutical ingredient (API), given its usage in treating some …