Origins of lifetime health around the time of conception: causes and consequences
Parental environmental factors, including diet, body composition, metabolism, and stress,
affect the health and chronic disease risk of people throughout their lives, as captured in the …
affect the health and chronic disease risk of people throughout their lives, as captured in the …
[HTML][HTML] Obesity as disruptor of the female fertility
E Silvestris, G De Pergola, R Rosania… - Reproductive Biology and …, 2018 - Springer
Both obesity and overweight are increasing worldwide and have detrimental influences on
several human body functions including the reproductive health. In particular, obese women …
several human body functions including the reproductive health. In particular, obese women …
[HTML][HTML] Obesity induces ovarian inflammation and reduces oocyte quality
In the United States, 36.5% of women between the ages of 20 and 39 years are obese. This
obesity results in not only metabolic disorders including type II diabetes and cardiovascular …
obesity results in not only metabolic disorders including type II diabetes and cardiovascular …
[HTML][HTML] Single-cell reconstruction of follicular remodeling in the human adult ovary
X Fan, M Bialecka, I Moustakas, E Lam… - Nature …, 2019 - nature.com
The ovary is perhaps the most dynamic organ in the human body, only rivaled by the uterus.
The molecular mechanisms that regulate follicular growth and regression, ensuring ovarian …
The molecular mechanisms that regulate follicular growth and regression, ensuring ovarian …
[HTML][HTML] Female obesity and infertility: outcomes and regulatory guidance
S Marinelli, G Napoletano, M Straccamore… - Acta Bio Medica …, 2022 - ncbi.nlm.nih.gov
Obesity has been associated with reduced fertility, although the dynamics and mechanisms
which link excess weight to reduced fertility are not yet fully clarified. Obese women …
which link excess weight to reduced fertility are not yet fully clarified. Obese women …
[HTML][HTML] Maternal low-grade chronic inflammation and intrauterine programming of health and disease
F Parisi, R Milazzo, VM Savasi, I Cetin - International journal of molecular …, 2021 - mdpi.com
Overweight and obesity during pregnancy have been associated with increased birth
weight, childhood obesity, and noncommunicable diseases in the offspring, leading to a …
weight, childhood obesity, and noncommunicable diseases in the offspring, leading to a …
[HTML][HTML] Deciphering metabolic heterogeneity by single-cell analysis
Single-cell analysis provides insights into cellular heterogeneity and dynamics of individual
cells. This Feature highlights recent developments in key analytical techniques suited for …
cells. This Feature highlights recent developments in key analytical techniques suited for …
[HTML][HTML] A narrative review: CXC chemokines influence immune surveillance in obesity and obesity-related diseases: Type 2 diabetes and nonalcoholic fatty liver …
Adipose tissue develops lipids, aberrant adipokines, chemokines, and pro-inflammatory
cytokines as a consequence of the low-grade systemic inflammation that characterizes …
cytokines as a consequence of the low-grade systemic inflammation that characterizes …
[HTML][HTML] New insights and potential therapeutic interventions in metabolic diseases
VJ Clemente-Suárez, A Martín-Rodríguez… - International Journal of …, 2023 - mdpi.com
Endocrine homeostasis and metabolic diseases have been the subject of extensive
research in recent years. The development of new techniques and insights has led to a …
research in recent years. The development of new techniques and insights has led to a …
Obesity and oocyte quality: significant implications for ART and emerging mechanistic insights
The prevalence of obesity in adults worldwide, and specifically in women of reproductive
age, is concerning given the risks to fertility posed by the increased risk of type 2 diabetes …
age, is concerning given the risks to fertility posed by the increased risk of type 2 diabetes …