During oncogenesis, cancer not only escapes the body's regulatory mechanisms, but also
gains the ability to affect local and systemic homeostasis. Specifically, tumors produce …

The nervous system regulates tissue stem and precursor populations throughout life.
Parallel to roles in development, the nervous system is emerging as a critical regulator of …

Reactive oxygen species (ROS)‐mediated tumor catalytic therapy is typically hindered by
gap junction proteins that form cell‐to‐cell channels to remove cytotoxic ROS, thereby …

Starvation therapy has been considered a promising strategy in cancer treatment for altering
the tumor microenvironment (TME) and causing a cascade of therapeutic effects. However, it …

Biomaterials can modulate the local immune and repair-supportive microenvironments to
promote peripheral nerve regeneration. Inorganic bioceramics have been widely used for …

Cancer cells rewire their metabolism to survive during cancer progression. In this context,
tumour metabolic heterogeneity arises and develops in response to diverse environmental …

Neurotransmitters are key modulators in neuro-immune circuits and have been linked to
tumor progression. Medullary thyroid cancer (MTC), an aggressive neuroendocrine tumor …

This review delves into the most recent research on the metabolic adaptability of cancer
cells and examines how their metabolic functions can impact their progression into …

Perineural invasion (PNI) is the process through which tumors invade and interact with
nerves. The dynamic changes in the nerves caused by PNI may induce disturbing …

The channels from the superfamily of transient receptor potential (TRP) activated by reactive
oxygen species (ROS) can be defined as redox channels. Those with the best exposure of …