Bioactive secondary metabolites from plant sources: types, synthesis, and their therapeutic uses

BM Twaij, MN Hasan - International Journal of Plant Biology, 2022 - mdpi.com
Plants are the source of various photochemicals; metabolites are used in medicinal and
environmental sectors as well as being widely used in commercial and pharmaceutical …

Diversity in chemical structures and biological properties of plant alkaloids

S Bhambhani, KR Kondhare, AP Giri - Molecules, 2021 - mdpi.com
Phytochemicals belonging to the group of alkaloids are signature specialized metabolites
endowed with countless biological activities. Plants are armored with these naturally …

The past, present and future of anti-malarial medicines

EG Tse, M Korsik, MH Todd - Malaria journal, 2019 - Springer
Great progress has been made in recent years to reduce the high level of suffering caused
by malaria worldwide. Notably, the use of insecticide-treated mosquito nets for malaria …

Plasmodium—a brief introduction to the parasites causing human malaria and their basic biology

S Sato - Journal of physiological anthropology, 2021 - Springer
Malaria is one of the most devastating infectious diseases of humans. It is problematic
clinically and economically as it prevails in poorer countries and regions, strongly hindering …

Antimalarial drug discovery: Progress and approaches

JL Siqueira-Neto, KJ Wicht, K Chibale… - Nature Reviews Drug …, 2023 - nature.com
Recent antimalarial drug discovery has been a race to produce new medicines that
overcome emerging drug resistance, whilst considering safety and improving dosing …

Malaria: the past and the present

J Talapko, I Škrlec, T Alebić, M Jukić, A Včev - Microorganisms, 2019 - mdpi.com
Malaria is a severe disease caused by parasites of the genus Plasmodium, which is
transmitted to humans by a bite of an infected female mosquito of the species Anopheles …

Antiviral, antibacterial, antifungal, and antiparasitic properties of propolis: A review

F Zulhendri, K Chandrasekaran, M Kowacz, M Ravalia… - Foods, 2021 - mdpi.com
Propolis is a complex phytocompound made from resinous and balsamic material harvested
by bees from flowers, branches, pollen, and tree exudates. Humans have used propolis …

[HTML][HTML] Current and future threats to human health in the Anthropocene

S Tong, H Bambrick, PJ Beggs, L Chen, Y Hu… - Environment …, 2022 - Elsevier
It has been widely recognised that the threats to human health from global environmental
changes (GECs) are increasing in the Anthropocene epoch, and urgent actions are required …

[HTML][HTML] The TWIK2 potassium efflux channel in macrophages mediates NLRP3 inflammasome-induced inflammation

A Di, S Xiong, Z Ye, RKS Malireddi, S Kometani… - Immunity, 2018 - cell.com
Potassium (K+) efflux across the plasma membrane is thought to be an essential mechanism
for ATP-induced NLRP3 inflammasome activation, yet the identity of the efflux channel has …

Role of plant alkaloids on human health: A review of biological activities

B Debnath, WS Singh, M Das, S Goswami… - Materials today …, 2018 - Elsevier
Alkaloids are plant secondary metabolite. They are well known nitrogen-containing natural
bioactive compounds. Cutting edge research is going on alkaloids to unravel novel …