Sulfur and its functional groups are major players in an area of exciting research taking
place in modern polymer and materials science, both in academia and industry. In fact …

Since the elucidation of the molecular structure of nucleic acids and understanding of their
role in encoding and translating genetic information into biological function, 1 the knowledge …

Unlike natural macromolecules (eg, nucleic acids and proteins) possessing precisely
defined molar mass, chain sequence, chirality, and topology, synthetic polymers are typically …

Natural macromolecules, such as proteins and nucleic acids, display various complex
functionalities in biological systems. These functionalities depend on the macromolecular …

Polymeric vehicles are versatile tools for therapeutic gene delivery. Many polymers—when
assembled with nucleic acids into vehicles—can protect the cargo from degradation and …

In the last decade, the field of sequence‐defined polymers and related ultraprecise,
monodisperse synthetic macromolecules has grown exponentially. In the early stage, mainly …

Polyethylenimine (PEI) is a gold standard polycationic transfectant. However, the highly
efficient transfecting activity of PEI and many of its derivatives is accompanied by serious …

The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR‐
associated protein 9 (Cas9) system offers great opportunities for the treatment of numerous …

This review describes recent changes and progress in the field of polymer bioconjugation (ie
covalent attachment of synthetic polymers to biological entities such as nucleic acids …

Long, multifunctional sequence-defined oligomers were obtained on solid support from a
protecting-group-free two-step iterative protocol, based on the inherent reactivity of a readily …