Role of the gut–brain axis in energy and glucose metabolism

HR Wachsmuth, SN Weninger, FA Duca - Experimental & molecular …, 2022 - nature.com
The gastrointestinal tract plays a role in the development and treatment of metabolic
diseases. During a meal, the gut provides crucial information to the brain regarding …

Food components and dietary habits: keys for a healthy gut microbiota composition

E Rinninella, M Cintoni, P Raoul, LR Lopetuso… - Nutrients, 2019 - mdpi.com
The gut microbiota is a changing ecosystem, containing trillions of bacteria, continuously
shaped by many factors, such as dietary habits, seasonality, lifestyle, stress, antibiotics use …

Leaky gut: effect of dietary fiber and fats on microbiome and intestinal barrier

H Usuda, T Okamoto, K Wada - International journal of molecular …, 2021 - mdpi.com
Intestinal tract is the boundary that prevents harmful molecules from invading into the
mucosal tissue, followed by systemic circulation. Intestinal permeability is an index for …

Role of gut microbiota-generated short-chain fatty acids in metabolic and cardiovascular health

ES Chambers, T Preston, G Frost, DJ Morrison - Current nutrition reports, 2018 - Springer
Abstract Purpose of this Review This review assesses the latest evidence linking short-chain
fatty acids (SCFA) with host metabolic health and cardiovascular disease (CVD) risk and …

Intestinal barrier and permeability in health, obesity and NAFLD

P Portincasa, L Bonfrate, M Khalil, MD Angelis… - Biomedicines, 2021 - mdpi.com
The largest surface of the human body exposed to the external environment is the gut. At this
level, the intestinal barrier includes luminal microbes, the mucin layer, gastrointestinal …

Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

JS Loh, WQ Mak, LKS Tan, CX Ng, HH Chan… - … and Targeted Therapy, 2024 - nature.com
The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

[HTML][HTML] The role of diet in shaping human gut microbiota

E Rinninella, E Tohumcu, P Raoul, M Fiorani… - Best Practice & …, 2023 - Elsevier
Gut microbiota plays a fundamental role within human health, and exerts key functions
within the human body. Diet is one of the most powerful modulators of gut microbiota …

Oligofructose improves small intestinal lipid-sensing mechanisms via alterations to the small intestinal microbiota

SN Weninger, C Herman, RK Meyer, ET Beauchemin… - Microbiome, 2023 - Springer
Background Upper small intestinal dietary lipids activate a gut-brain axis regulating energy
homeostasis. The prebiotic, oligofructose (OFS) improves body weight and adiposity during …

The influence of dietary factors on the gut microbiota

E Nova, S Gómez-Martinez, R González-Soltero - Microorganisms, 2022 - mdpi.com
There is increasing evidence that diet influences the relationship between gut microbiota
and individual health outcomes. Nutrient intake affects the composition of the gut microbial …

Dietary inulin alleviates diverse stages of type 2 diabetes mellitus via anti-inflammation and modulating gut microbiota in db/db mice

K Li, L Zhang, J Xue, X Yang, X Dong, L Sha, H Lei… - Food & function, 2019 - pubs.rsc.org
Type 2 diabetes mellitus (T2DM) is closely correlated with chronic low-grade inflammation
and gut dysbiosis. Prebiotic inulin (INU) is conducive to modulate gut dysbiosis. However …